预防儿童和青少年糖尿病设备引起皮肤问题的皮肤护理计划:一项集群控制干预研究。

IF 14.8 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes Care Pub Date : 2023-10-01 DOI:10.2337/dc23-0462
Anna Korsgaard Berg, Annemarie Cecilie Grauslund, Fiona Sørensen, Steffen Ullitz Thorsen, Jacob P Thyssen, Claus Zachariae, Jannet Svensson
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引用次数: 0

摘要

目的:输送胰岛素和测量血糖水平的糖尿病设备是现代1型糖尿病治疗的基石。然而,它们的使用经常与皮肤问题的发展有关,特别是湿疹和伤口。适当的皮肤护理可以预防皮肤问题,但缺乏来自介入研究的循证信息。提供这些信息是本研究的目的。研究设计和方法:这项集群控制干预研究测试了基本皮肤护理计划的疗效(包括使用脂质霜、去除和避免消毒)。共有170名患有1型糖尿病的儿童和青少年被纳入,并被分配到干预组(n=112)或对照组(n=58)。在装置启动后的第一年,每季度对参与者进行一次检查,在非盲环境中进行临床评估和访谈。结果:与46.6%的对照组参与者相比,33.6%的干预组参与者观察到湿疹或伤口(绝对差异,12.9%[95%CI-28.7%,2.9%];P=0.010)。与对照组相比,干预组伤口发展的调整几率降低了71%(伤口的优势比0.29[95%CI0.12,0.68];P=0.005)。总共只观察到8例感染,尽管建议省略消毒,但在干预组中没有更高的频率。结论:这些数据表明,我们的基本皮肤护理计划部分预防了糖尿病设备引起的皮肤反应。然而,需要使用其他粘合剂、贴片和/或乳液类型的更多预防策略来优化预防。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Skin Care Program to Prevent Skin Problems due to Diabetes Devices in Children and Adolescents: A Cluster-Controlled Intervention Study.

Objective: Diabetes devices that deliver insulin and measure blood glucose levels are cornerstones in modern treatment of type 1 diabetes. However, their use is frequently associated with the development of skin problems, particularly eczema and wounds. Proper skin care may prevent skin problems, yet evidence-based information from interventional studies is missing. Providing this information is the aim of this study.

Research design and methods: This cluster-controlled intervention study tested the efficacy of a basic skin care program (including use of lipid cream, removal, and avoidance of disinfection). A total of 170 children and adolescents with type 1 diabetes were included and assigned either to the intervention group (n = 112) or the control group (n = 58). Participants were seen quarterly the first year after device initiation, with clinical assessment and interview in an unblinded setting.

Results: Eczema or wounds were observed in 33.6% of the intervention group compared with 46.6% of control participants (absolute difference, 12.9% [95% CI -28.7%, 2.9%]; P = 0.10). The adjusted odds of wound development were decreased by 71% in the intervention compared with control group (for wounds, odds ratio 0.29 [95% CI 0.12, 0.68]; P = 0.005). In total, only eight infections were seen, without a higher frequency in the intervention group, despite advice to omit disinfection.

Conclusions: These data indicate our basic skin care program partially prevented diabetes device-induced skin reactions. However, more preventive strategies with other adhesives, patches, and/or types of lotions are needed for optimized prevention.

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来源期刊
Diabetes Care
Diabetes Care 医学-内分泌学与代谢
CiteScore
27.80
自引率
4.90%
发文量
449
审稿时长
1 months
期刊介绍: The journal's overarching mission can be captured by the simple word "Care," reflecting its commitment to enhancing patient well-being. Diabetes Care aims to support better patient care by addressing the comprehensive needs of healthcare professionals dedicated to managing diabetes. Diabetes Care serves as a valuable resource for healthcare practitioners, aiming to advance knowledge, foster research, and improve diabetes management. The journal publishes original research across various categories, including Clinical Care, Education, Nutrition, Psychosocial Research, Epidemiology, Health Services Research, Emerging Treatments and Technologies, Pathophysiology, Complications, and Cardiovascular and Metabolic Risk. Additionally, Diabetes Care features ADA statements, consensus reports, review articles, letters to the editor, and health/medical news, appealing to a diverse audience of physicians, researchers, psychologists, educators, and other healthcare professionals.
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