[自身免疫性溶血是胰腺癌和弥漫大 B 细胞淋巴瘤同时伴有嗜血细胞组织细胞增多症的最初表现：病例报告]。

Zhonghua nei ke za zhi Pub Date : 2023-07-01 DOI:10.3760/cma.j.cn112138-20220624-00477

C W Qi, Q Li, W Xiao, Z Y Luan

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[Autoimmune hemolysis as the initial manifestation in simultaneous pancreatic cancer and diffuse large B-cell lymphoma with hemophagocyticlymphohistocytosis:a case report].

自身免疫性溶血性贫血和噬血细胞综合征常继发于病毒感染、血液系统恶性肿瘤及自身免疫病，特别是与B-淋巴瘤相关性噬血细胞综合征相比，T/NK-淋巴瘤相关性噬血细胞综合征发病率高、EB病毒颗粒检出率高，实体肿瘤合并自身免疫性溶血性贫血和噬血细胞综合征的报道也罕见。本文报道一例老年男性，入院时表现为自身免疫性溶血性贫血，给予糖皮质激素治疗，病情仍迅速进展，经病理证实同时患有小B淋巴细胞白血病和胰体部腺癌，并因反复黑便行肠镜及免疫组织化学（IHC）检查确诊为横结肠脾区EB病毒阳性弥漫大B细胞淋巴瘤，最终因消化道出血抢救无效。.

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