儿童营养与表观遗传学。

Q1 Medicine
Catherine Lynn T Silao
{"title":"儿童营养与表观遗传学。","authors":"Catherine Lynn T Silao","doi":"10.1159/000528991","DOIUrl":null,"url":null,"abstract":"<p><p>Studies have shown a dramatic increase in the incidence and the prevalence of chronic diseases such as type 2 diabetes mellitus and cardiovascular disorders over the last several decades. Environmental triggers and nutrition are considered major contributors to this increase. The first 1,000 days of life, which is the period between conception and the first 2 years of age, is considered the time for environmental factors, such as nutrition, to exert their positive and most crucial effects on a child's health. Nutrigenomics, the study of how genes and food components interact, looks into diet-altering disease development by modulating processes involved with the onset, progression, and severity of disease. These factors affecting the development of these chronic diseases are thought to be mediated by epigenetic mechanisms, which are heritable and reversible, and carry genetic information without changing the nucleotide sequence of the genome and are also mediated by maternal and postnatal nutrition.</p>","PeriodicalId":18986,"journal":{"name":"Nestle Nutrition Institute workshop series","volume":"97 ","pages":"1-10"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Child's Nutrition and Epigenetics.\",\"authors\":\"Catherine Lynn T Silao\",\"doi\":\"10.1159/000528991\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Studies have shown a dramatic increase in the incidence and the prevalence of chronic diseases such as type 2 diabetes mellitus and cardiovascular disorders over the last several decades. Environmental triggers and nutrition are considered major contributors to this increase. The first 1,000 days of life, which is the period between conception and the first 2 years of age, is considered the time for environmental factors, such as nutrition, to exert their positive and most crucial effects on a child's health. Nutrigenomics, the study of how genes and food components interact, looks into diet-altering disease development by modulating processes involved with the onset, progression, and severity of disease. These factors affecting the development of these chronic diseases are thought to be mediated by epigenetic mechanisms, which are heritable and reversible, and carry genetic information without changing the nucleotide sequence of the genome and are also mediated by maternal and postnatal nutrition.</p>\",\"PeriodicalId\":18986,\"journal\":{\"name\":\"Nestle Nutrition Institute workshop series\",\"volume\":\"97 \",\"pages\":\"1-10\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nestle Nutrition Institute workshop series\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000528991\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nestle Nutrition Institute workshop series","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000528991","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

研究表明,在过去的几十年里,慢性疾病如2型糖尿病和心血管疾病的发病率和流行率急剧增加。环境因素和营养被认为是这一增长的主要原因。生命的头1 000天,即从怀孕到2岁之间的这段时间,被认为是营养等环境因素对儿童健康发挥积极和最关键影响的时期。营养基因组学是一门研究基因和食物成分如何相互作用的学科,它通过调节与疾病的发病、进展和严重程度有关的过程,来研究改变饮食的疾病的发展。这些影响这些慢性疾病发展的因素被认为是由表观遗传机制介导的,这些机制是可遗传和可逆的,并且在不改变基因组核苷酸序列的情况下携带遗传信息,并且还由母体和产后营养介导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Child's Nutrition and Epigenetics.

Studies have shown a dramatic increase in the incidence and the prevalence of chronic diseases such as type 2 diabetes mellitus and cardiovascular disorders over the last several decades. Environmental triggers and nutrition are considered major contributors to this increase. The first 1,000 days of life, which is the period between conception and the first 2 years of age, is considered the time for environmental factors, such as nutrition, to exert their positive and most crucial effects on a child's health. Nutrigenomics, the study of how genes and food components interact, looks into diet-altering disease development by modulating processes involved with the onset, progression, and severity of disease. These factors affecting the development of these chronic diseases are thought to be mediated by epigenetic mechanisms, which are heritable and reversible, and carry genetic information without changing the nucleotide sequence of the genome and are also mediated by maternal and postnatal nutrition.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Nestle Nutrition Institute workshop series
Nestle Nutrition Institute workshop series Medicine-Pediatrics, Perinatology and Child Health
CiteScore
4.30
自引率
0.00%
发文量
22
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信