鼻窦抬高术预防性抗生素治疗:系统综述。

IF 1.7 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
Ángel-Orión Salgado-Peralvo, Alvaro Garcia-Sanchez, Naresh Kewalramani, Mario Romandini, Eugenio Velasco-Ortega
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引用次数: 0

摘要

目的:研究在上颌窦抬高手术中使用预防性抗生素治疗是否能降低移植物感染和/或种植体失败率(主要结局),并确定相关的最佳方案(次要结局)。材料和方法:检索2006年12月至2021年12月期间的MEDLINE(通过PubMed)、Web of Science、Scopus、LILACS和OpenGrey数据库。纳入了至少50例患者的前瞻性和回顾性比较临床研究,并以英文发表。排除了动物研究、系统综述和荟萃分析、叙述性文献综述、书籍、病例报告、给编辑的信件和评论。已确定研究的评估、数据提取和偏倚风险由两位审稿人独立进行。如有需要,我们会联系作者。收集的数据以描述性方法报告。结果:共有12项研究符合纳入标准。唯一一项比较使用抗生素与不使用抗生素的回顾性研究显示,在种植体失败方面没有统计学上的显著差异;然而,没有关于鼻窦感染率的数据报道。唯一一项比较不同疗程抗生素的随机临床试验(仅手术当天与术后额外7天)报告两组间鼻窦感染率无统计学显著差异。结论:没有足够的证据支持在鼻窦抬高手术中使用或不使用预防性抗生素治疗,也没有足够的证据支持任何方案优于其他方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preventive Antibiotic Therapy in Sinus Elevation Procedures: A Systematic Review.

Purpose: To study whether the use of preventive antibiotic therapy reduces the sinus graft infection and/or dental implant failure rates in maxillary sinus elevation surgeries (primary outcome), and to identify the associated best protocol (secondary outcome). Materials and Methods: The MEDLINE (via PubMed), Web of Science, Scopus, LILACS, and OpenGrey databases were searched between December 2006 and December 2021. Prospective and retrospective comparative clinical studies with at least 50 patients and published in English were included. Animal studies, systematic reviews and meta-analyses, narrative literature reviews, books, case reports, letters to the editor, and commentaries were excluded. Assessment of the identified studies, data extraction, and risk of bias were performed independently by two reviewers. Authors were contacted if required. Collected data were reported by descriptive methods. Results: A total of 12 studies fulfilled the inclusion criteria. The only retrospective study comparing the use of antibiotics vs no use of them showed no statistically significant differences for implant failure; however, no data were reported for sinus infection rates. The only randomized clinical trial comparing different courses of antibiotics (only the day of surgery vs 7 additional postoperative days) reported no statistically significant differences between groups in terms of sinus infection rate. Conclusion: Not enough evidence is available to support either the use or nonuse of preventive antibiotic therapy for sinus elevation surgeries or to support the superiority of any protocol over others.

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来源期刊
CiteScore
3.30
自引率
5.00%
发文量
115
审稿时长
6 months
期刊介绍: Edited by Steven E. Eckert, DDS, MS ISSN (Print): 0882-2786 ISSN (Online): 1942-4434 This highly regarded, often-cited journal integrates clinical and scientific data to improve methods and results of oral and maxillofacial implant therapy. It presents pioneering research, technology, clinical applications, reviews of the literature, seminal studies, emerging technology, position papers, and consensus studies, as well as the many clinical and therapeutic innovations that ensue as a result of these efforts. The editorial board is composed of recognized opinion leaders in their respective areas of expertise and reflects the international reach of the journal. Under their leadership, JOMI maintains its strong scientific integrity while expanding its influence within the field of implant dentistry. JOMI’s popular regular feature "Thematic Abstract Review" presents a review of abstracts of recently published articles on a specific topical area of interest each issue.
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