Roberto González L, Andrés Schaub C, Felipe Alarcón O, Rodrigo Reyes M, Aleck Stockins L, Enrique Seguel S, Alejandra Riquelme U, Sebastián Barra M, Diego Saldivia Z, Patricio Madrid C, Alejandro Pérez G, Emilio Alarcón C
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Survival data were obtained from the Chilean Civil Registry Office and a complete ten-year follow up was accomplished. Survival was analyzed with Kaplan-Meier method with log-rank test and Cox regression.</p><p><strong>Results: </strong>Operative mortality occurred in 13 patients (2%). Survival at 1, 3, 5 and 10 years was 97, 94, 91 and 76%, respectively. One, 3, 5 and 10-year free of cardiovascular death survival was 98, 97, 95 y 89%, respectively. Factors associated with long-term survival were chronic kidney disease in hemodialysis (Hazard ratio (HR) 7.9; 95% confidence intervals (CI) 4.6-13.6), chronic obstructive pulmonary disease (HR 2.3; 95% CI 1.4-3.7), chronic arterial occlusive disease (HR 2.2; 95% CI 1.4-3.4) and diabetes mellitus (HR 1.9; 95% CI 1.4-2.6). According to EuroSCORE, 10-year survival was 86, 75 and 62% (p < 0.01) in low, medium and high-risk patients, respectively.</p><p><strong>Conclusions: </strong>These patients had a 10-year survival comparable to large international series. 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引用次数: 0
摘要
背景:冠状动脉旁路移植术(CABG)是广泛的冠状动脉疾病患者的治疗选择。目的:描述孤立性冠脉搭桥患者的总体生存率和与较低长期生存率相关的因素。材料和方法:对2006年1月至2008年12月在某公立医院行冠脉搭桥的患者进行队列分析。回顾我院1003例心脏手术的数据库和手术记录。其中,658例患者(年龄62±9岁)行单独冠脉搭桥,其中男性516例(78%)。生存数据从智利民事登记处获得,并完成了为期10年的完整随访。生存率分析采用Kaplan-Meier法、log-rank检验和Cox回归。结果:手术死亡13例(2%)。1年、3年、5年和10年的生存率分别为97%、94%、91%和76%。1年、3年、5年和10年无心血管死亡生存率分别为98%、97%、95%和89%。与长期生存相关的因素是血液透析患者的慢性肾脏疾病(危险比(HR) 7.9;95%可信区间(CI) 4.6-13.6),慢性阻塞性肺疾病(HR 2.3;95% CI 1.4-3.7),慢性动脉闭塞性疾病(HR 2.2;95% CI 1.4-3.4)和糖尿病(HR 1.9;95% ci 1.4-2.6)。根据EuroSCORE,低、中、高风险患者的10年生存率分别为86%、75%和62% (p < 0.01)。结论:这些患者的10年生存率与大型国际系列相当。确定了与较低10年生存率相关的组。
[Risk factors associated with 10-year survival after coronary artery bypass grafting].
Background: Coronary artery bypass grafting (CABG) is the treatment of choice for a broad spectrum of patients with coronary disease.
Aim: To describe global survival and factors associated with lower long-term survival in patients operated with isolated CABG.
Material and methods: Analysis of a cohort of patients who underwent CABG between January 2006 and December 2008 at a public hospital. The database and operation records of 1.003 cardiac surgeries were reviewed. Of these, an isolated CABG was performed in 658 patients aged 62 ± 9 years including 516 male (78%). Survival data were obtained from the Chilean Civil Registry Office and a complete ten-year follow up was accomplished. Survival was analyzed with Kaplan-Meier method with log-rank test and Cox regression.
Results: Operative mortality occurred in 13 patients (2%). Survival at 1, 3, 5 and 10 years was 97, 94, 91 and 76%, respectively. One, 3, 5 and 10-year free of cardiovascular death survival was 98, 97, 95 y 89%, respectively. Factors associated with long-term survival were chronic kidney disease in hemodialysis (Hazard ratio (HR) 7.9; 95% confidence intervals (CI) 4.6-13.6), chronic obstructive pulmonary disease (HR 2.3; 95% CI 1.4-3.7), chronic arterial occlusive disease (HR 2.2; 95% CI 1.4-3.4) and diabetes mellitus (HR 1.9; 95% CI 1.4-2.6). According to EuroSCORE, 10-year survival was 86, 75 and 62% (p < 0.01) in low, medium and high-risk patients, respectively.
Conclusions: These patients had a 10-year survival comparable to large international series. Groups associated with lower 10-year survival were identified.
期刊介绍:
La Revista Médica de Chile publica trabajos originales sobre temas de interés médico y de Ciencias Biomédicas, dando preferencia a los relacionados con la Medicina Interna y sus especialidades derivadas.
Publicada mensualmente, desde 1872, por la Sociedad Médica de Santiago.
La abreviatura de su título es Rev Med Chile, que debe ser usado en bibliografías, notas al pié de página, leyendas y referencias bibliográficas.