Diana Athonvarangkul, Kaicheng Wang, Yanhong Deng, Silvio E Inzucchi, Adam Mayerson
{"title":"糖尿病患者短期接触嵌有远红外线热敏微粒的纺织品可改善肢体组织的氧合。","authors":"Diana Athonvarangkul, Kaicheng Wang, Yanhong Deng, Silvio E Inzucchi, Adam Mayerson","doi":"10.1177/14791641231170282","DOIUrl":null,"url":null,"abstract":"<p><strong>Methods: </strong>A single-center, prospective, randomized, placebo-controlled, double-blinded, crossover study of 32 subjects with either type 1 or type 2 DM. An active FIR wrap followed by a placebo wrap (or vice versa) was applied to the arm, calf, ankle, and forefoot for 60 min each with continuous TcPO<sub>2</sub> measurements. The treatment effect of the active versus placebo wrap was estimated using a linear mixed effect model adjusted for period, sequence, baseline value, and anatomic site.</p><p><strong>Results: </strong>The active FIR wrap increased mean TcPO<sub>2</sub> at the arm (2.6 ± 0.8 mmHg, <i>p</i> = .002), calf (1.5 ± 0.7 mmHg, <i>p</i> = .03), and ankle (1.7 ± 0.8 mmHg, <i>p</i> = .04) and composite of all sites (1.4 ± 0.5 mmHg, <i>p</i> = .002) after 60 min. The estimated treatment effect was significant for the active FIR wrap at the calf (1.5 ± 0.7 mmHg, <i>p</i> = .045) and in composite of all sites (1.2 ± 0.5 mmHg, <i>p</i> = .013).</p><p><strong>Conclusion: </strong>Short-term exposure to FIR textiles improves peripheral tissue oxygenation in patients with diabetes.</p>","PeriodicalId":11092,"journal":{"name":"Diabetes & Vascular Disease Research","volume":"20 2","pages":"14791641231170282"},"PeriodicalIF":2.8000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/05/10.1177_14791641231170282.PMC10123901.pdf","citationCount":"0","resultStr":"{\"title\":\"Improved extremity tissue oxygenation with short-term exposure to textiles embedded with far infrared light emitting thermoactive particles in patients with diabetes mellitus.\",\"authors\":\"Diana Athonvarangkul, Kaicheng Wang, Yanhong Deng, Silvio E Inzucchi, Adam Mayerson\",\"doi\":\"10.1177/14791641231170282\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Methods: </strong>A single-center, prospective, randomized, placebo-controlled, double-blinded, crossover study of 32 subjects with either type 1 or type 2 DM. An active FIR wrap followed by a placebo wrap (or vice versa) was applied to the arm, calf, ankle, and forefoot for 60 min each with continuous TcPO<sub>2</sub> measurements. The treatment effect of the active versus placebo wrap was estimated using a linear mixed effect model adjusted for period, sequence, baseline value, and anatomic site.</p><p><strong>Results: </strong>The active FIR wrap increased mean TcPO<sub>2</sub> at the arm (2.6 ± 0.8 mmHg, <i>p</i> = .002), calf (1.5 ± 0.7 mmHg, <i>p</i> = .03), and ankle (1.7 ± 0.8 mmHg, <i>p</i> = .04) and composite of all sites (1.4 ± 0.5 mmHg, <i>p</i> = .002) after 60 min. The estimated treatment effect was significant for the active FIR wrap at the calf (1.5 ± 0.7 mmHg, <i>p</i> = .045) and in composite of all sites (1.2 ± 0.5 mmHg, <i>p</i> = .013).</p><p><strong>Conclusion: </strong>Short-term exposure to FIR textiles improves peripheral tissue oxygenation in patients with diabetes.</p>\",\"PeriodicalId\":11092,\"journal\":{\"name\":\"Diabetes & Vascular Disease Research\",\"volume\":\"20 2\",\"pages\":\"14791641231170282\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/05/10.1177_14791641231170282.PMC10123901.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diabetes & Vascular Disease Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/14791641231170282\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diabetes & Vascular Disease Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/14791641231170282","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Improved extremity tissue oxygenation with short-term exposure to textiles embedded with far infrared light emitting thermoactive particles in patients with diabetes mellitus.
Methods: A single-center, prospective, randomized, placebo-controlled, double-blinded, crossover study of 32 subjects with either type 1 or type 2 DM. An active FIR wrap followed by a placebo wrap (or vice versa) was applied to the arm, calf, ankle, and forefoot for 60 min each with continuous TcPO2 measurements. The treatment effect of the active versus placebo wrap was estimated using a linear mixed effect model adjusted for period, sequence, baseline value, and anatomic site.
Results: The active FIR wrap increased mean TcPO2 at the arm (2.6 ± 0.8 mmHg, p = .002), calf (1.5 ± 0.7 mmHg, p = .03), and ankle (1.7 ± 0.8 mmHg, p = .04) and composite of all sites (1.4 ± 0.5 mmHg, p = .002) after 60 min. The estimated treatment effect was significant for the active FIR wrap at the calf (1.5 ± 0.7 mmHg, p = .045) and in composite of all sites (1.2 ± 0.5 mmHg, p = .013).
Conclusion: Short-term exposure to FIR textiles improves peripheral tissue oxygenation in patients with diabetes.
期刊介绍：
Diabetes & Vascular Disease Research is the first international peer-reviewed journal to unite diabetes and vascular disease in a single title. The journal publishes original papers, research letters and reviews. This journal is a member of the Committee on Publication Ethics (COPE)
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