在静脉切开术前一小时摄入咖啡对常规生化测试结果没有显著的临床变化。

IF 3.8 3区 医学 Q1 MEDICAL LABORATORY TECHNOLOGY
Silvia F Benozzi, Gisela Unger, Amparo Campion, Pablo G Milano, Graciela L Pennacchiotti
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引用次数: 0

摘要

导读:虽然目前的指南建议在静脉切开术前不要喝咖啡,但我们的假设是,喝咖啡不会影响生化和血液学测试结果的临床解释。材料与方法:27名志愿者分别在基础状态(T0)和喝咖啡后1h (T1)进行研究。常规血液学(Sysmex-XN1000分析仪)和生化参数(Vitros 4600分析仪)的研究。比较结果采用Wilcoxon检验(P < 0.05)。当平均百分比差异(MD%)高于参考变化值(RCV)时,认为临床改变。结果:咖啡摄入产生统计学意义,但不具有临床意义:我)增加血红蛋白(P = 0.009),意味着细胞血红蛋白浓度(P = 0.044),中性粒细胞(P = 0.001),白蛋白(P = 0.001),血清总蛋白(P = 0.000),胆固醇(P = 0.025),高密度脂蛋白胆固醇(P = 0.007),尿酸(P = 0.011),钙(P = 0.001),钾(P = 0.010)、天冬氨酸转氨酶(P = 0.001)、淀粉酶(P = 0.026)和乳酸脱氢酶(P = 0.001),和2)减少意味着细胞体积(P = 0.002),红细胞分布宽度(P = 0.001),嗜酸性粒细胞(P = 0.002)、淋巴细胞(P = 0.001)、肌酐(P = 0.001)、总胆红素(P = 0.012)、磷(P = 0.001)、镁(P = 0.007)和氯化物(P = 0.001)。结论:在采血前1小时喝一杯咖啡对常规生化和血液学检查结果没有明显的临床变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Coffee intake one hour prior to phlebotomy produces no clinically significant changes in routine biochemical test results.

Coffee intake one hour prior to phlebotomy produces no clinically significant changes in routine biochemical test results.

Introduction: Although current guidelines recommend not drinking coffee prior to phlebotomy, our hypothesis is that drinking coffee does not affect the clinical interpretation of biochemical and haematological test results.

Materials and methods: Twenty-seven volunteers were studied in basal state (T0) and 1h after (T1) drinking coffee. Routine haematological (Sysmex-XN1000 analyser) and biochemistry parameters (Vitros 4600 analyser) were studied. Results were compared using the Wilcoxon test (P < 0.05). A clinical change was considered when mean percent difference (MD%) was higher than the reference change value (RCV).

Results: Coffee intake produced statistically, but not clinically, significant: i) increases in haemoglobin (P = 0.009), mean cell haemoglobin concentration (P = 0.044), neutrophils (P = 0.001), albumin (P = 0.001), total protein (P = 0.000), cholesterol (P = 0.025), high density lipoprotein cholesterol (P = 0.007), uric acid (P = 0.011), calcium (P = 0.001), potassium (P = 0.010), aspartate aminotransferase (P = 0.001), amylase (P = 0.026), and lactate dehydrogenase (P = 0.001), and ii) decreases in mean cell volume (P = 0.002), red cell distribution width (P = 0.001), eosinophils (P = 0.002), and lymphocytes (P = 0.001), creatinine (P = 0.001), total bilirubin (P = 0.012), phosphorus (P = 0.001), magnesium (P = 0.007), and chloride (P = 0.001).

Conclusion: Drinking a cup of coffee 1 hour prior to phlebotomy produces no clinically significant changes in routine biochemical and haematological test results.

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来源期刊
Biochemia Medica
Biochemia Medica 医学-医学实验技术
CiteScore
5.50
自引率
3.00%
发文量
70
审稿时长
>12 weeks
期刊介绍: Biochemia Medica is the official peer-reviewed journal of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Journal provides a wide coverage of research in all aspects of clinical chemistry and laboratory medicine. Following categories fit into the scope of the Journal: general clinical chemistry, haematology and haemostasis, molecular diagnostics and endocrinology. Development, validation and verification of analytical techniques and methods applicable to clinical chemistry and laboratory medicine are welcome as well as studies dealing with laboratory organization, automation and quality control. Journal publishes on a regular basis educative preanalytical case reports (Preanalytical mysteries), articles dealing with applied biostatistics (Lessons in biostatistics) and research integrity (Research integrity corner).
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