骨髓瘤的负担:疾病评估的新方法

IF 2.9 3区教育学 Q1 EDUCATION, SCIENTIFIC DISCIPLINES

Hematology. American Society of Hematology. Education Program Pub Date : 2022-12-09 DOI:10.1182/hematology.2022000348

Matthew Ho, Taxiarchis Kourelis

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引用次数: 0

摘要

多发性骨髓瘤(MM)的新疗法提高了患者的常规完全缓解(CR)率。然而，CR患者可能有高度异质性的结果。评估治疗后残余疾病负担的新颖和更敏感的方法将有助于更好地预测这一群体，并且在理想情况下，允许基于反应深度的个性化治疗调整。在这里，我们回顾了评估骨髓瘤负担的新的骨髓、外周血和成像方法，并讨论了将这些方法纳入日常临床实践的机会和局限性。

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The burden of myeloma: novel approaches to disease assessment.

Novel therapies in multiple myeloma (MM) have increased the rates of conventional complete remission (CR) in patients. However, patients in CR can have highly heterogeneous outcomes. Novel and more sensitive methods of assessing residual disease burden after therapy will help prognosticate this group better and, ideally, allow individualized therapy adjustments based on response depth in the future. Here, we review novel bone marrow, peripheral blood, and imaging methods for assessing myeloma burden and discuss the opportunities and limitations of incorporating these in everyday clinical practice.

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来源期刊

Hematology. American Society of Hematology. Education Program EDUCATION, SCIENTIFIC DISCIPLINES-HEMATOLOGY

CiteScore

4.70

自引率

3.30%

发文量

期刊介绍： Hematology, the ASH Education Program, is published annually by the American Society of Hematology (ASH) in one volume per year.