在噪音与功能之间:走向非规范翻译组的分类。

IF 9 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Cell Systems Pub Date : 2023-05-17 DOI:10.1016/j.cels.2023.04.004

Zachary Ardern, Md Hassan Uz-Zaman

引用次数: 0

摘要

真核生物基因组普遍被翻译，但典型基因之外的翻译序列的特性却知之甚少。《细胞系统》杂志上的一项新研究揭示了一种大型翻译体，它不受显著的进化限制，但仍然是多种细胞系统的活跃部分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Between noise and function: Toward a taxonomy of the non-canonical translatome.

Eukaryotic genomes are pervasively translated, but the properties of translated sequences outside of canonical genes are poorly understood. A new study in Cell Systems reveals a large translatome that is not under significant evolutionary constraint but is still an active part of diverse cellular systems.

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来源期刊

Cell Systems Medicine-Pathology and Forensic Medicine

CiteScore

16.50

自引率

1.10%

发文量

审稿时长

42 days

期刊介绍： In 2015, Cell Systems was founded as a platform within Cell Press to showcase innovative research in systems biology. Our primary goal is to investigate complex biological phenomena that cannot be simply explained by basic mathematical principles. While the physical sciences have long successfully tackled such challenges, we have discovered that our most impactful publications often employ quantitative, inference-based methodologies borrowed from the fields of physics, engineering, mathematics, and computer science. We are committed to providing a home for elegant research that addresses fundamental questions in systems biology.