卡马西平治疗中的全血细胞减少症:一种罕见且严重的简单预防实体。

Pub Date : 2023-01-01 Epub Date: 2023-03-27 DOI:10.4103/ijabmr.ijabmr_530_22
Akansha Bhardwaj, Rashmi Prakash, Dimple Gupta, Nimmi Jose
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引用次数: 0

摘要

卡马西平是精神科常用的药物,用于部分癫痫发作、全身强直阵挛性癫痫发作、混合性癫痫发作模式、三叉神经痛相关疼痛、急性躁狂和混合躁狂状态等适应症。然而,这种药物也有一系列不良反应,如恶心、呕吐、腹泻、头晕、低钠血症、头痛和口干。一个罕见的严重副作用包括“卡马西平诱导的全血细胞减少症”。在本病例报告中,我们希望强调一例已知的精神分裂症患者,他服用卡马西平片作为辅助治疗,随后出现全血细胞减少。在清除了犯罪特工后,她的计数逐渐恢复正常。通过报告这一案例,我们希望强调定期监测全血细胞计数的重要性,而这一点往往被忽视。此外,对患者进行关于定期血液监测和坚持的重要性的心理教育对提高他们的依从性具有相当重要的意义。通过确保采取这种简单的预防措施,可以通过早期发现警告信号来避免这种严重和不寻常的副作用。
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Pancytopenia in Carbamazepine Therapy: A Rare and Serious Entity with Simple Prevention.

Carbamazepine is a commonly used drug in psychiatric settings used for indications such as partial seizures, generalized tonic-clonic seizures, mixed seizure patterns, pain associated with trigeminal neuralgia, acute manic, and mixed manic states. However, this drug comes with its own series of adverse effects such as nausea, vomiting, diarrhea, dizziness, hyponatremia, headaches, and dry mouth. One serious side effect which is rarely documented includes "carbamazepine-induced pancytopenia." In this case report, we wish to highlight a known case of schizophrenia, who was taking tablet carbamazepine as adjunctive treatment and subsequently developed pancytopenia. On removing the offending agent, her counts gradually returned to normal. By reporting this case, we wish to emphasize regarding the importance of regular monitoring of complete blood count, which often gets neglected. Furthermore, psychoeducating patients regarding regular blood monitoring and the importance of adherence holds considerable importance in enhancing their compliance. By ensuring such simple preventive measures, such serious and unusual side effects may be averted through early detection of warning signs.

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