垂体结核瘤伴全垂体功能减退,伪装成垂体腺瘤。

IF 1.3 4区 医学 Q4 CLINICAL NEUROLOGY
Neuropathology Pub Date : 2023-12-01 Epub Date: 2023-05-30 DOI:10.1111/neup.12925
Adil Aziz Khan, Sana Ahuja, Shaivy Malik, Saba Naaz, Sufian Zaheer
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引用次数: 0

摘要

下丘脑-垂体轴结核极为罕见。全垂体功能减退的表现在一个病例的卖方结核是一个更罕见的发生。我们提出一个44岁的男子谁提出投诉头痛和右侧视力下降六个月。激素谱显示垂体前叶检测异常提示全垂体功能低下。脑磁共振成像显示鞍区肿块,尺寸为1.8 × 1.5 × 1.3 cm,鞍上延伸提示垂体腺瘤。组织病理学检查显示坏死背景下多发上皮样细胞肉芽肿伴朗汉斯巨细胞及混合性炎性浸润。Zeihl - Neelson染色显示有抗酸杆菌。因此,最终诊断为垂体结核瘤,患者开始接受抗结核治疗。正确诊断鞍区结核是非常重要的,因为治疗方法完全不同,患者通常对治疗反应良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pituitary tuberculoma with panhypopituitarism masquerading as a pituitary adenoma.

Tuberculosis of the hypothalamo-pituitary axis is extremely uncommon. The presentation of panhypopituitarism in a case of sellar tuberculosis is an even rarer occurrence. We present a case of a 44-year-old man who presented with complaints of headache and right-sided diminution of vision for six months. A hormone profile showed abnormal anterior pituitary assay suggestive of panhypopituitarism. Magnetic Resonance imaging of the brain showed a sellar mass measuring 1.8 × 1.5 × 1.3 cm with suprasellar extension suggestive of a pituitary adenoma. Histopathological examination showed multiple epithelioid cell granulomas along with Langhans giant cells and mixed inflammatory infiltrates against a necrotic background. Zeihl Neelson stain demonstrated the presence of acid-fast bacilli. Thus, a final diagnosis of pituitary tuberculoma was made, and the patient started on antitubercular therapy. It is extremely important to correctly diagnose sellar tuberculosis as the treatment is entirely different, and the patient usually responds well to therapy.

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来源期刊
Neuropathology
Neuropathology 医学-病理学
CiteScore
4.10
自引率
4.30%
发文量
105
审稿时长
6-12 weeks
期刊介绍: Neuropathology is an international journal sponsored by the Japanese Society of Neuropathology and publishes peer-reviewed original papers dealing with all aspects of human and experimental neuropathology and related fields of research. The Journal aims to promote the international exchange of results and encourages authors from all countries to submit papers in the following categories: Original Articles, Case Reports, Short Communications, Occasional Reviews, Editorials and Letters to the Editor. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.
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