胃癌胰后淋巴结转移的危险因素及临床意义。

IF 0.5 4区医学 Q4 SURGERY

Cirugia Y Cirujanos Pub Date : 2023-05-08 DOI:10.24875/CIRU.22000270

Aydin Yavuz, Huseyin Gobut, Kursat Dikmen, Hasan Bostanci, Ahmet Cagri Buyukkasap, Osman Yuksel

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引用次数: 0

摘要

背景:胃癌患者胰后淋巴结转移的发生率不容忽视。目的:探讨胰后淋巴结(LN)转移的危险因素，探讨其临床意义。患者与方法:回顾性分析2012年6月至2017年6月237例胃癌患者的临床病理资料。结果:14例(5.9%)发生胰腺后淋巴结转移。有和没有胰腺后淋巴结转移的患者的中位生存期分别为13.1和25.7个月。根据单变量分析;肿瘤大小≥8cm、Bormann III/IV型、未分化型、存在血管淋巴浸润、浸润深度(pT4)、N3期、No. 3、No. 7、No. 8、No. 9、No. 12p淋巴结转移与胰腺后淋巴结转移相关。根据多变量分析;肿瘤大小≥8cm、Bormann III/IV型、未分化型、pT4、N3期、No. 9 LN转移、No. 12p LN转移是胰腺后淋巴结转移的独立预后因素。结论:胰腺后淋巴结转移是胃癌预后不良的因素。肿瘤大小(≥8cm)、Bormann III/IV型、未分化肿瘤、pT4、N3期、No 9、No 12p淋巴结转移是胰后淋巴结转移的危险因素。

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Risk factors and clinical significances for retropancreatic lymph node metastasis in gastric cancer patients.

Background: The incidence of retropancreatic lymph node metastasis in gastric cancer patients is not negligible.

Aim: The aim of present study was to determine the risk factors for retropancreatic lymph node (LN) metastasis and to investigate its clinical significance.

Patients and methods: Clinical pathologic data of 237 patients with gastric cancer between June 2012 and June 2017 were analyzed retrospectively.

Results: 14 patients (5.9%) had retropancreatic LN metastases. The median survival of patients with and without retropancreatic LN metastasis was 13.1 and 25.7 months. According to univariate analysis; tumor size ≥ 8 cm, Bormann type III/IV, undifferentiated type, presence of angiolymphatic invasion, depth of invasion (pT4), N3 stage, No. 3, No. 7, No. 8, No. 9, and No. 12p LN metastasis was found to be associated with retropancreatic LN metastasis. According to multivariate analysis; tumor size ≥ 8 cm, Bormann type III/IV, undifferentiated type, pT4, N3 stage, No. 9 LN metastasis, and No. 12p LN metastasis were found to be independent prognostic variables for retropancreatic LN metastasis.

Conclusion: Retropancreatic LN metastasis is a poor prognostic factor for gastric cancer. Tumor size (≥ 8 cm), Bormann type III/IV, undifferentiated tumor, pT4, N3 stage, and No. 9 and No. 12p LN metastasis are risk factors for metastasis to retropancreatic lymph node.

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来源期刊

Cirugia Y Cirujanos 医学-外科

CiteScore

0.90

自引率

20.00%

发文量

207

审稿时长

6-12 weeks

期刊介绍： Cirugía y Cirujanoses exponente del desarrollo académico, científico, médico, quirúrgico y tecnológico en materia de salud en México y en el ámbito internacional. Es una revista bimestral, open access, revisada por pares, que publica en español y en inglés (traducido sin coste para los autores) artículos científicos originales, casos clínicos, artículos de revisión de interés general y cartas al editor. Los artículos se seleccionan y publican siguiendo un riguroso análisis, de acuerdo con los estándares internacionalmente aceptados. Sus espacios están abiertos a los académicos, así como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos.