Mario Inacio , Patrick Esser , Junxian Li , Lei Xu , Hui Zeng , Rui He , Helen Dawes , Fang Liu
{"title":"步态的光谱参数将糖尿病患者与健康人区分开来。","authors":"Mario Inacio , Patrick Esser , Junxian Li , Lei Xu , Hui Zeng , Rui He , Helen Dawes , Fang Liu","doi":"10.1016/j.foot.2023.102038","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Diabetes mellitus (DM) is a clinical condition that affects gait performance and control in millions of individuals worldwide. Contrary to basic spatiotemporal parameters, gait-based spectral analysis may provide useful insights into gait neuromotor control. Hence, this study was set to investigate the spectral content of gait at the preferred speed in patients with DM.</p></div><div><h3>Methods</h3><p>Total 1117 individuals [658 DM and 649 healthy adults (HA)] performed a 10 m walk while wearing an inertial measurement unit over the fourth lumbar vertebra. Mann-Whitney-U test was used for between-group gait parameters comparisons.</p></div><div><h3>Results</h3><p>DM group had a slower step time (1.2%, <em>p</em> < 0.05) and gait speed (2.4%, <em>p</em> < 0.05) than HA. Additionally, DM individuals showed reduced dominant frequency (DM:0.24 <em>Hz vs</em> HA:0.25 <em>Hz o</em>n average, <em>p</em> < 0.05). Increased antero-posterior and vertical dominant frequency width (DM:1.73 <em>Hz vs</em> HA:1.76 <em>Hz o</em>n average, <em>p</em> < 0.05) and medio-lateral relative power spectral density at the dominant frequency (DM:6.19% <em>vs</em> HA:5.96%, <em>p</em> < 0.05).</p></div><div><h3>Conclusions</h3><p>It was demonstrated for the first time that the gait spectral content, not only corroborates spatiotemporal characteristics, but also provides further insight into their neuromotor control deficits in diabetic patients. Ultimately, this type of analysis in the diabetic population can help guide the therapeutic interventions to prevent diabetic foot.</p></div>","PeriodicalId":12349,"journal":{"name":"Foot","volume":"56 ","pages":"Article 102038"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Spectral parameters of gait differentiate diabetic patients from healthy individuals\",\"authors\":\"Mario Inacio , Patrick Esser , Junxian Li , Lei Xu , Hui Zeng , Rui He , Helen Dawes , Fang Liu\",\"doi\":\"10.1016/j.foot.2023.102038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Diabetes mellitus (DM) is a clinical condition that affects gait performance and control in millions of individuals worldwide. Contrary to basic spatiotemporal parameters, gait-based spectral analysis may provide useful insights into gait neuromotor control. Hence, this study was set to investigate the spectral content of gait at the preferred speed in patients with DM.</p></div><div><h3>Methods</h3><p>Total 1117 individuals [658 DM and 649 healthy adults (HA)] performed a 10 m walk while wearing an inertial measurement unit over the fourth lumbar vertebra. Mann-Whitney-U test was used for between-group gait parameters comparisons.</p></div><div><h3>Results</h3><p>DM group had a slower step time (1.2%, <em>p</em> < 0.05) and gait speed (2.4%, <em>p</em> < 0.05) than HA. Additionally, DM individuals showed reduced dominant frequency (DM:0.24 <em>Hz vs</em> HA:0.25 <em>Hz o</em>n average, <em>p</em> < 0.05). Increased antero-posterior and vertical dominant frequency width (DM:1.73 <em>Hz vs</em> HA:1.76 <em>Hz o</em>n average, <em>p</em> < 0.05) and medio-lateral relative power spectral density at the dominant frequency (DM:6.19% <em>vs</em> HA:5.96%, <em>p</em> < 0.05).</p></div><div><h3>Conclusions</h3><p>It was demonstrated for the first time that the gait spectral content, not only corroborates spatiotemporal characteristics, but also provides further insight into their neuromotor control deficits in diabetic patients. Ultimately, this type of analysis in the diabetic population can help guide the therapeutic interventions to prevent diabetic foot.</p></div>\",\"PeriodicalId\":12349,\"journal\":{\"name\":\"Foot\",\"volume\":\"56 \",\"pages\":\"Article 102038\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Foot\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0958259223000792\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Health Professions\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Foot","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0958259223000792","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Health Professions","Score":null,"Total":0}
Spectral parameters of gait differentiate diabetic patients from healthy individuals
Background
Diabetes mellitus (DM) is a clinical condition that affects gait performance and control in millions of individuals worldwide. Contrary to basic spatiotemporal parameters, gait-based spectral analysis may provide useful insights into gait neuromotor control. Hence, this study was set to investigate the spectral content of gait at the preferred speed in patients with DM.
Methods
Total 1117 individuals [658 DM and 649 healthy adults (HA)] performed a 10 m walk while wearing an inertial measurement unit over the fourth lumbar vertebra. Mann-Whitney-U test was used for between-group gait parameters comparisons.
Results
DM group had a slower step time (1.2%, p < 0.05) and gait speed (2.4%, p < 0.05) than HA. Additionally, DM individuals showed reduced dominant frequency (DM:0.24 Hz vs HA:0.25 Hz on average, p < 0.05). Increased antero-posterior and vertical dominant frequency width (DM:1.73 Hz vs HA:1.76 Hz on average, p < 0.05) and medio-lateral relative power spectral density at the dominant frequency (DM:6.19% vs HA:5.96%, p < 0.05).
Conclusions
It was demonstrated for the first time that the gait spectral content, not only corroborates spatiotemporal characteristics, but also provides further insight into their neuromotor control deficits in diabetic patients. Ultimately, this type of analysis in the diabetic population can help guide the therapeutic interventions to prevent diabetic foot.
期刊介绍：
The Foot is an international peer-reviewed journal covering all aspects of scientific approaches and medical and surgical treatment of the foot. The Foot aims to provide a multidisciplinary platform for all specialties involved in treating disorders of the foot. At present it is the only journal which provides this inter-disciplinary opportunity. Primary research papers cover a wide range of disorders of the foot and their treatment, including diabetes, vascular disease, neurological, dermatological and infectious conditions, sports injuries, biomechanics, bioengineering, orthoses and prostheses.
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