Kai-Yang Xue, Fei Quan, Jia-Xuan Tang, Cai-Hong Xiao, Chun-Xia Lu, Jin Cui
{"title":"[竹基灸治疗慢性疲劳综合征：随机对照试验]。","authors":"Kai-Yang Xue, Fei Quan, Jia-Xuan Tang, Cai-Hong Xiao, Chun-Xia Lu, Jin Cui","doi":"10.13703/j.0255-2930.20220818-k0001","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To observe the clinical efficacy of bamboo-based medicinal moxibustion for chronic fatigue syndrome (CFS), and to preliminarily explore its action mechanism.</p><p><strong>Methods: </strong>Sixty-four patients with CFS were randomly divided into a moxibustion group (32 cases, 1 case dropped off, 1 case excluded) and an acupuncture group (32 cases, 2 cases dropped off). The patients in the moxibustion group were treated with bamboo-based medicinal moxibustion, while the patients in the acupuncture group were treated with routine acupuncture. Both groups were treated once a day, 6 days as a course of treatment with 1 day interval, for a total of 2 courses of treatment. Before treatment, 1 and 2 courses into treatment and in the follow-up of 14 days after treatment, the fatigue scale-14 (FS-14) and somatic and psychological health report (SPHERE) scores were observed in the two groups. Before and after treatment, the contents of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub>, CD<sup>+</sup><sub>8</sub> of peripheral blood T lymphocyte subsets were measured and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio was calculated; the clinical efficacy of the two groups was compared.</p><p><strong>Results: </strong>Compared before treatment, the FS-14 and SPHERE scores in the two groups were decreased 1 and 2 courses into treatment and in the follow-up (<i>P</i><0.01), and the FS-14 and SPHERE scores in the moxibustion group were lower than those in the acupuncture group (<i>P</i><0.01, <i>P</i><0.05). Compared before treatment, the contents of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub> and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio in the moxibustion group were increased after treatment (<i>P</i><0.01). There was no significant difference of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub>, CD<sup>+</sup><sub>8</sub> and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio between before and after treatment in the acupuncture group (<i>P</i>>0.05). After treatment, the contents of CD<sup>+</sup><sub>3</sub> and CD<sup>+</sup><sub>4</sub> in the moxibustion group were higher than those in the acupuncture group (<i>P</i><0.05). The total effective rate was 93.3% (28/30) in the moxibustion group, which was higher than 73.3% (22/30) in the acupuncture group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Bamboo-based medicinal moxibustion could improve the physical and mental fatigue symptoms and psychological status in patients with CFS. Its effect may be related to regulating the contents of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub> of peripheral blood T lymphocyte subsets and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio.</p>","PeriodicalId":23967,"journal":{"name":"Zhongguo zhen jiu = Chinese acupuncture & moxibustion","volume":"43 5","pages":"493-8"},"PeriodicalIF":0.0000,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Bamboo-based medicinal moxibustion for chronic fatigue syndrome: a randomized controlled trial].\",\"authors\":\"Kai-Yang Xue, Fei Quan, Jia-Xuan Tang, Cai-Hong Xiao, Chun-Xia Lu, Jin Cui\",\"doi\":\"10.13703/j.0255-2930.20220818-k0001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To observe the clinical efficacy of bamboo-based medicinal moxibustion for chronic fatigue syndrome (CFS), and to preliminarily explore its action mechanism.</p><p><strong>Methods: </strong>Sixty-four patients with CFS were randomly divided into a moxibustion group (32 cases, 1 case dropped off, 1 case excluded) and an acupuncture group (32 cases, 2 cases dropped off). The patients in the moxibustion group were treated with bamboo-based medicinal moxibustion, while the patients in the acupuncture group were treated with routine acupuncture. Both groups were treated once a day, 6 days as a course of treatment with 1 day interval, for a total of 2 courses of treatment. Before treatment, 1 and 2 courses into treatment and in the follow-up of 14 days after treatment, the fatigue scale-14 (FS-14) and somatic and psychological health report (SPHERE) scores were observed in the two groups. Before and after treatment, the contents of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub>, CD<sup>+</sup><sub>8</sub> of peripheral blood T lymphocyte subsets were measured and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio was calculated; the clinical efficacy of the two groups was compared.</p><p><strong>Results: </strong>Compared before treatment, the FS-14 and SPHERE scores in the two groups were decreased 1 and 2 courses into treatment and in the follow-up (<i>P</i><0.01), and the FS-14 and SPHERE scores in the moxibustion group were lower than those in the acupuncture group (<i>P</i><0.01, <i>P</i><0.05). Compared before treatment, the contents of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub> and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio in the moxibustion group were increased after treatment (<i>P</i><0.01). There was no significant difference of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub>, CD<sup>+</sup><sub>8</sub> and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio between before and after treatment in the acupuncture group (<i>P</i>>0.05). After treatment, the contents of CD<sup>+</sup><sub>3</sub> and CD<sup>+</sup><sub>4</sub> in the moxibustion group were higher than those in the acupuncture group (<i>P</i><0.05). The total effective rate was 93.3% (28/30) in the moxibustion group, which was higher than 73.3% (22/30) in the acupuncture group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Bamboo-based medicinal moxibustion could improve the physical and mental fatigue symptoms and psychological status in patients with CFS. Its effect may be related to regulating the contents of CD<sup>+</sup><sub>3</sub>, CD<sup>+</sup><sub>4</sub> of peripheral blood T lymphocyte subsets and CD<sup>+</sup><sub>4</sub>/CD<sup>+</sup><sub>8</sub> ratio.</p>\",\"PeriodicalId\":23967,\"journal\":{\"name\":\"Zhongguo zhen jiu = Chinese acupuncture & moxibustion\",\"volume\":\"43 5\",\"pages\":\"493-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-05-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zhongguo zhen jiu = Chinese acupuncture & moxibustion\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.13703/j.0255-2930.20220818-k0001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhongguo zhen jiu = Chinese acupuncture & moxibustion","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13703/j.0255-2930.20220818-k0001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Bamboo-based medicinal moxibustion for chronic fatigue syndrome: a randomized controlled trial].
Objective: To observe the clinical efficacy of bamboo-based medicinal moxibustion for chronic fatigue syndrome (CFS), and to preliminarily explore its action mechanism.
Methods: Sixty-four patients with CFS were randomly divided into a moxibustion group (32 cases, 1 case dropped off, 1 case excluded) and an acupuncture group (32 cases, 2 cases dropped off). The patients in the moxibustion group were treated with bamboo-based medicinal moxibustion, while the patients in the acupuncture group were treated with routine acupuncture. Both groups were treated once a day, 6 days as a course of treatment with 1 day interval, for a total of 2 courses of treatment. Before treatment, 1 and 2 courses into treatment and in the follow-up of 14 days after treatment, the fatigue scale-14 (FS-14) and somatic and psychological health report (SPHERE) scores were observed in the two groups. Before and after treatment, the contents of CD+3, CD+4, CD+8 of peripheral blood T lymphocyte subsets were measured and CD+4/CD+8 ratio was calculated; the clinical efficacy of the two groups was compared.
Results: Compared before treatment, the FS-14 and SPHERE scores in the two groups were decreased 1 and 2 courses into treatment and in the follow-up (P<0.01), and the FS-14 and SPHERE scores in the moxibustion group were lower than those in the acupuncture group (P<0.01, P<0.05). Compared before treatment, the contents of CD+3, CD+4 and CD+4/CD+8 ratio in the moxibustion group were increased after treatment (P<0.01). There was no significant difference of CD+3, CD+4, CD+8 and CD+4/CD+8 ratio between before and after treatment in the acupuncture group (P>0.05). After treatment, the contents of CD+3 and CD+4 in the moxibustion group were higher than those in the acupuncture group (P<0.05). The total effective rate was 93.3% (28/30) in the moxibustion group, which was higher than 73.3% (22/30) in the acupuncture group (P<0.05).
Conclusion: Bamboo-based medicinal moxibustion could improve the physical and mental fatigue symptoms and psychological status in patients with CFS. Its effect may be related to regulating the contents of CD+3, CD+4 of peripheral blood T lymphocyte subsets and CD+4/CD+8 ratio.
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