{"title":"美国中年研究中的重复思维、认知和全身炎症。","authors":"Elana M Gloger, Suzanne C Segerstrom","doi":"10.1080/08870446.2022.2092104","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Poor cognition increases risk for negative health outcomes, and this may be explained by associations with systemic inflammation. Previously, amount of repetitive thought (Total RT) interacted with IQ to predict interleukin-6 (IL-6) in older adults. This study continued the investigation of repetitive thought (RT) as an element involved in the effect of cognition on inflammation.</p><p><strong>Design: </strong>Participants (<i>N</i> = 164) came from the Midlife in the United States Refresher project (M<sub>age</sub> = 45.33, SD = 11.51, ranges = 25-74; 48.2% female; 85% Caucasian). Cognition was assessed via telephone, inflammatory biomarkers (IL-6, C-reactive protein (CRP), and tumour-necrosis factor-alpha (TNF- α)) analysed after blood draw, and RT derived from daily diary data.</p><p><strong>Results: </strong>Cognition significantly interacted with RT valence (<i>p</i> = .009) to explain CRP after covariate adjustment. Better cognition and more negative RT valence was associated with lower CRP (<i>β</i> = -0.190 [-.387, .008]). Worse cognition and more negative RT valence was associated with higher CRP (<i>β</i> = 0.133 [-.031, .297]). No significant effects were found for IL-6 or TNF-α.</p><p><strong>Conclusion: </strong>RT may interact with cognition to affect different inflammatory biomarkers. Those with worse cognition may benefit more from skills related to regulating thought than those with better cognition.</p>","PeriodicalId":20718,"journal":{"name":"Psychology & Health","volume":" ","pages":"651-669"},"PeriodicalIF":2.4000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026601/pdf/","citationCount":"0","resultStr":"{\"title\":\"Repetitive thought, cognition, and systemic inflammation in the midlife in the United States study.\",\"authors\":\"Elana M Gloger, Suzanne C Segerstrom\",\"doi\":\"10.1080/08870446.2022.2092104\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Poor cognition increases risk for negative health outcomes, and this may be explained by associations with systemic inflammation. Previously, amount of repetitive thought (Total RT) interacted with IQ to predict interleukin-6 (IL-6) in older adults. This study continued the investigation of repetitive thought (RT) as an element involved in the effect of cognition on inflammation.</p><p><strong>Design: </strong>Participants (<i>N</i> = 164) came from the Midlife in the United States Refresher project (M<sub>age</sub> = 45.33, SD = 11.51, ranges = 25-74; 48.2% female; 85% Caucasian). Cognition was assessed via telephone, inflammatory biomarkers (IL-6, C-reactive protein (CRP), and tumour-necrosis factor-alpha (TNF- α)) analysed after blood draw, and RT derived from daily diary data.</p><p><strong>Results: </strong>Cognition significantly interacted with RT valence (<i>p</i> = .009) to explain CRP after covariate adjustment. Better cognition and more negative RT valence was associated with lower CRP (<i>β</i> = -0.190 [-.387, .008]). Worse cognition and more negative RT valence was associated with higher CRP (<i>β</i> = 0.133 [-.031, .297]). No significant effects were found for IL-6 or TNF-α.</p><p><strong>Conclusion: </strong>RT may interact with cognition to affect different inflammatory biomarkers. Those with worse cognition may benefit more from skills related to regulating thought than those with better cognition.</p>\",\"PeriodicalId\":20718,\"journal\":{\"name\":\"Psychology & Health\",\"volume\":\" \",\"pages\":\"651-669\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026601/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psychology & Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/08870446.2022.2092104\",\"RegionNum\":3,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/6/27 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHOLOGY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychology & Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/08870446.2022.2092104","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/6/27 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PSYCHOLOGY, MULTIDISCIPLINARY","Score":null,"Total":0}
Repetitive thought, cognition, and systemic inflammation in the midlife in the United States study.
Objective: Poor cognition increases risk for negative health outcomes, and this may be explained by associations with systemic inflammation. Previously, amount of repetitive thought (Total RT) interacted with IQ to predict interleukin-6 (IL-6) in older adults. This study continued the investigation of repetitive thought (RT) as an element involved in the effect of cognition on inflammation.
Design: Participants (N = 164) came from the Midlife in the United States Refresher project (Mage = 45.33, SD = 11.51, ranges = 25-74; 48.2% female; 85% Caucasian). Cognition was assessed via telephone, inflammatory biomarkers (IL-6, C-reactive protein (CRP), and tumour-necrosis factor-alpha (TNF- α)) analysed after blood draw, and RT derived from daily diary data.
Results: Cognition significantly interacted with RT valence (p = .009) to explain CRP after covariate adjustment. Better cognition and more negative RT valence was associated with lower CRP (β = -0.190 [-.387, .008]). Worse cognition and more negative RT valence was associated with higher CRP (β = 0.133 [-.031, .297]). No significant effects were found for IL-6 or TNF-α.
Conclusion: RT may interact with cognition to affect different inflammatory biomarkers. Those with worse cognition may benefit more from skills related to regulating thought than those with better cognition.
期刊介绍：
Psychology & Health promotes the study and application of psychological approaches to health and illness. The contents include work on psychological aspects of physical illness, treatment processes and recovery; psychosocial factors in the aetiology of physical illnesses; health attitudes and behaviour, including prevention; the individual-health care system interface particularly communication and psychologically-based interventions. The journal publishes original research, and accepts not only papers describing rigorous empirical work, including meta-analyses, but also those outlining new psychological approaches and interventions in health-related fields.
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