骨关节炎的疼痛治疗方案。

Q4 Medicine
Olga Šléglová
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引用次数: 0

摘要

骨关节炎是关节和脊柱最常见的疾病之一,其特点是软骨开始发生退行性变化。关节病变会导致疼痛、僵硬、肿胀以及正常关节功能的丧失。国际上有多项建议涉及骨关节炎治疗方法的选择。然而,由于目前还没有有效的因果治疗方法能使疾病得到缓解,因此这是一个复杂的问题。甚至连有效而安全地治疗骨关节炎最常见的疼痛问题的可能性也非常有限。目前国际上关于骨关节炎治疗的所有建议都一致认为,非药物治疗和选择综合方法治疗骨关节炎具有至关重要的作用。药物治疗包括非阿片类镇痛药、阿片类药物、对症慢作用骨关节炎药物或关节内皮质类固醇。一个新的趋势是通过联合使用现有的镇痛药来最大限度地发挥它们的潜力。使用作用机制互补的不同类别的药物,可以在减少单个药物剂量的情况下更好地实现有效镇痛。使用固定的联合用药也很有优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pain treatment options for osteoarthritis.

Osteoarthritis is one of the most common diseases of the joints and spine and is characterized by degenerative changes starting in the cartilage. Joint changes cause pain, stiffness, swelling, and a loss of normal joint function. Several international recommendations address the choice of treatment methods for osteoarthritis. However, because there is still no effective causal treatment leading to a remission of the disease, this is a complex issue. Even the possibilities of effective but safe treatment of pain, which is the most common problem accompanying osteoarthritis, are very limited. All current international recommendations for the treatment of osteoarthritis agree on the crucial role of non-pharmacological treatment and the choice of a comprehensive approach to the treatment of osteoarthritis. Pharmacological treatment includes non-opioid analgesics, opioids, symptomatic slow-acting osteoarthritis drugs, or intra-articular corticosteroids. A new trend is to maximize the potential of existing analgesics by combining them. Using drugs from different classes with complementary mechanisms of action provides a better opportunity for effective analgesia at reduced doses of individual agents. The use of fixed combinations is also advantageous.

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来源期刊
Vnitrni lekarstvi
Vnitrni lekarstvi Medicine-Internal Medicine
CiteScore
0.50
自引率
0.00%
发文量
104
期刊介绍: Vnitřní lékařství je tiskovým orgánem České internistické společnosti České lékařské společnosti Jana Evangelisty Purkyně a Slovenskej internistickej spoločnosti Slovenskej lekárskej spoločnosti. Je vydáván nepřetržitě od roku 1955. Časopis vychází jako měsíčník, tedy 12krát do roka a podle potřeby jsou v běžném ročníku vydávána jeho suplementa, která jsou obsahově zaměřena k určitému tématu. Tematicky je časopis zaměřen široce na oblast interní medicíny se zvláštní pozorností ke kardiologii, diabetologii a poruchám metabolizmu.
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