肠脑相互作用紊乱中食物相关症状的潜在机制:研究和临床实践的进展

IF 3.2 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Esther Colomier , Joost P. Algera , Karen Van den Houte , Magnus Simrén , Jan Tack
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引用次数: 0

摘要

一组患有肠脑相互作用障碍(DGBI)的患者报告了腹痛、气体相关症状、消化不良症状和餐后便便或尿急等症状。因此,包括富含纤维或限制性饮食在内的几种饮食疗法已经在肠易激综合征、功能性腹胀或腹胀以及功能性消化不良患者中进行了研究。然而,文献中对食物相关症状的潜在机制的研究很少。因此,这篇综述聚焦于这些潜在的机制,并解释了营养感知和品尝、身体因素、对食物的吸收不良或过敏样反应的作用及其与微生物群的相互作用。此外,它强调了未来关于DGBI患者食物相关症状的研究和临床实践的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Mechanisms underlying food-related symptoms in disorders of gut-brain interaction: Course ahead in research and clinical practice

Mechanisms underlying food-related symptoms in disorders of gut-brain interaction: Course ahead in research and clinical practice

A subgroup of patients with a disorder of gut-brain interaction (DGBI) report symptoms such as abdominal pain, gas-related symptoms, dyspeptic symptoms and loose stool or urgency after meal intake. Therefore, the effect of several dietary therapies including fibre-rich or restrictive diets have already been studied in patients with irritable bowel syndrome, functional abdominal bloating or distention, and functional dyspepsia. However, there is a paucity of studies in the literature on the mechanisms underlying food-related symptoms. Therefore, this review focuses on these potential mechanisms and explains the role of nutrient sensing and tasting, physical considerations, malabsorption or allergy-like reaction to food and its interaction with microbiota. In addition, it emphasizes the importance of future research and clinical practice regarding food-related symptoms in patients with a DGBI.

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来源期刊
CiteScore
5.50
自引率
0.00%
发文量
23
审稿时长
69 days
期刊介绍: Each topic-based issue of Best Practice & Research Clinical Gastroenterology will provide a comprehensive review of current clinical practice and thinking within the specialty of gastroenterology.
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