葡萄糖前驱治疗在颞下颌关节内部紊乱的治疗中有益吗？系统回顾。

IF 2 4区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-04-25 DOI:10.1080/08869634.2023.2204042

Mariam M Bahgat, Ahmed M Abdel-Hamid

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引用次数: 0

摘要

目的：总结葡萄糖作为前驱药物治疗颞下颌关节内紊乱（TMJ-ID）的疗效。方法：采用PubMed/MEDLINE、Cochrane数据库和谷歌Scholar数据库自成立至2022年8月的电子检索，执行“人口、干预、比较、结果”（PICO）策略。仅纳入随机临床试验，研究高渗葡萄糖前驱疗法（HDPT）治疗TMJ-ID。两名独立审稿人评估了研究的合格性，并进行了随后的数据提取。结果：系统检索到392篇研究，只有8篇文章符合入选条件，共纳入286例患者；72%为女性，28%为男性。提取的数据显示葡萄糖对关节疼痛和最大开口（MMO）有积极的影响，患者满意度高。结论：HDPT可以有效缓解TMD症状，因为它可以减轻疼痛，改善关节功能障碍，并增加长达12个月的MMO。

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Is dextrose prolotherapy beneficial in the management of temporomandibular joint internal derangement? A systematic review.

Objective: To highlight the current knowledge of the efficacy of dextrose as a prolotherapy agent in managing temporomandibular joint internal derangement (TMJ-ID).

Methods: A "Population, Intervention, Comparison, Outcome" (PICO) strategy was executed using an electronic search through PubMed/MEDLINE, Cochrane databases, and Google Scholar from their inception to August 2022. Only randomized clinical trials investigating the treatment of TMJ-ID with hypertonic dextrose prolotherapy (HDPT) were included. Two independent reviewers assessed the eligibility of the studies with subsequent data extraction.

Results: The systematic search identified 392 studies, and only 8 articles were considered eligible for selection, with a total of 286 patients; 72% were females, and 28% were males. The extracted data showed positive effects of dextrose on joint pain and maximum mouth opening (MMO) with high patient satisfaction.

Conclusion: HDPT can be effective in relieving TMD symptoms as it reduces pain, improves joint dysfunction, and increases MMO up to 12 months.

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来源期刊

Cranio-The Journal of Craniomandibular & Sleep Practice DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.50

自引率

12.50%

发文量

审稿时长

>12 weeks

期刊介绍： CRANIO: The Journal of Craniomandibular & Sleep Practice is the oldest and largest journal in the world devoted to temporomandibular disorders, and now also includes articles on all aspects of sleep medicine. The Journal is multidisciplinary in its scope, with editorial board members from all areas of medicine and dentistry, including general dentists, oral surgeons, orthopaedists, radiologists, chiropractors, professors and behavioural scientists, physical therapists, acupuncturists, osteopathic and ear, nose and throat physicians. CRANIO publishes commendable works from outstanding researchers and clinicians in their respective fields. The multidisciplinary format allows individuals practicing with a TMD emphasis to stay abreast of related disciplines, as each issue presents multiple topics from overlapping areas of interest. CRANIO''s current readership (thousands) is comprised primarily of dentists; however, many physicians, physical therapists, chiropractors, osteopathic physicians and other related specialists subscribe and contribute to the Journal.