[多发性硬化症患者的临床、人口和心理特征对其身体健康相关生活质量的影响]。

Q3 Medicine
Psychiatrike = Psychiatriki Pub Date : 2024-06-28 Epub Date: 2023-02-10 DOI:10.22365/jpsych.2023.001
Anthi Amaslidou, Ioanna Ierodiakonou-Benou, Christos Bakirtzis, Ioannis Nikolaidis, Theano Tatsi, Nikolaos Grigoriadis, Ioannis Nimatoudis
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引用次数: 0

摘要

多发性硬化症(MS)是中枢神经系统的一种慢性脱髓鞘和神经退行性疾病,症状多样,病程不定。多发性硬化症影响日常生活的多个方面,由于会导致一定程度的残疾,因此可能会导致生活质量下降,包括心理和身体健康方面。在这项研究中,我们调查了与身体健康生活质量(PHQOL)相关的人口统计学因素、临床因素以及主要是个人和心理因素的作用。我们的样本包括 90 名确诊的多发性硬化症患者,使用的工具有用于评估 PHQOL 的 MSQoL-54、用于评估防御方式和机制的 DSQ-88 和 LSI、用于评估抑郁的 BDI-II、用于评估焦虑的 STAI、用于测量协调感的 SOC-29 和用于评估家庭关系的 FES。影响 PHQOL 的重要人格因素是适应不良和自我牺牲的防御方式、移位和反应形成的防御机制、协调感,而从家庭环境来看,冲突对 PHQOL 有负面影响,表达能力对 PHQOL 有正面影响。然而,在回归分析中,这些因素都不重要。多元回归分析表明,抑郁症对 PHQOL 的影响最大(负相关)。此外,领取残疾津贴、子女人数、残疾状况和当年复发情况也是影响 PHQOL 的重要负面因素。经过逐级分析(其中排除了 BDI 和就业状况),最重要的变量是 EDSS、SOC 和过去一年的复发情况。这项研究证实了心理参数在 PHQOL 中发挥重要作用的假设,并强调了心理健康专业人员对每一位 PwMS 进行常规评估的重要性。不仅要了解精神症状,还要了解心理参数,以确定每个人如何适应疾病,从而影响其 PHQOL。因此,在个人或群体层面,甚至在家庭中进行有针对性的干预,可以提高他们的 QOL。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The role of clinical, demographic and psychological characteristics of people with multiple sclerosis in their physical health related quality of life].

Multiple Sclerosis (MS) is a chronic demyelinating and neurodegenerative disease of the central nervous system, with a variety of symptoms and uncertain course. It affects multiple facets of everyday life and since it results to some degree of disability, MS may cause deterioration of quality of life, both in mental and physical health. In this study, we investigated the role of demographic, clinical and, mostly, personal and psychological factors related to physical health quality of life (PHQOL). Our sample consisted of 90 patients with definite MS and the instruments used were: MSQoL-54 for PHQOL, DSQ-88 and LSI for the assessment of defense styles and mechanisms, BDI-II for depression, STAI for anxiety, SOC-29 as a measure of sense of coherence and FES for family relations. Important personality factors affecting PHQOL were the maladaptive and the self-sacrificing defense styles, the defense mechanisms of displacement and reaction formation, sense of coherence, while from the family environment, conflict affected PHQOL negatively and expressiveness positively. However, in the regression analysis none of these factors were found to be important. Multiple regression analysis showed the major impact of depression in PHQOL (negative correlation. Moreover, the fact that a person receives disability allowance, the number of the children, disability status and the event of a relapse in the current year, were also important negative factors for PHQOL. After a step-wise analysis, in which BDI and employment status were excluded, the most important variables were EDSS, SOC and relapse during the past year. This study confirms the hypothesis that psychological parameters play an important role in PHQOL and highlights the importance of the assessment of every PwMS by mental health professionals, as a routine. Not only psychiatric symptoms but also psychological parameters should be searched out in order to determine in which way each individual adjusts to the illness, thus impacting his PHQOL. As a result, targeted interventions, in personal or group level, or even in the family may enhance their QOL.

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来源期刊
Psychiatrike = Psychiatriki
Psychiatrike = Psychiatriki Medicine-Medicine (all)
CiteScore
2.60
自引率
0.00%
发文量
37
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