神经内科ICU非惊厥性癫痫持续状态患者并发症的频率和类型:对预后的影响

IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY
Nese Dericioglu, Cansu Ayvacioglu Cagan, Okan Sokmen, Ethem Murat Arsava, Mehmet Akif Topcuoglu
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引用次数: 0

摘要

目标。在重症监护病房(ICU)随访的非惊厥性癫痫持续状态(NCSE)患者并发症的发生频率和类型以及这些并发症对预后的影响尚不清楚。我们探讨了NCSE患者的并发症及其对预后的影响。方法。在回顾了2009年至2019年在ICU随访的所有连续患者的视频脑电图监测(VEEGM)报告后,我们确定了两组患者:1例NCSE患者(研究组)和2例因可能的NCSE而接受VEEGM但没有心电图记录的患者(无NCSE组)。对电子健康记录进行审查,以确定人口统计和临床数据、ICU护理时间、内科和外科并发症、药物治疗和结果。这些参数在两组间进行统计学比较。我们还研究了出院时影响预后的参数。结果。32例NCSE患者组成研究组。84%发生感染。半数以上患者接受气管插管、气管造口术或经皮内镜胃造口术。难治性NCSE与更频繁的并发症和更差的预后相关。研究组感染倾向较高(P = 0.059)。器官衰竭评分越高,ICU住院时间越长,预后越差(P结论。在ICU护理的NCSE患者并发症的频率相当高。除感染发生率较高外,其余并发症与ICU患者相似。提高医生对可修改参数的认识和及时干预可能有助于改善预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frequency and Types of Complications Encountered in Patients With Nonconvulsive Status Epilepticus in the Neurological ICU: Impact on Outcome.

Objectives. The frequency and types of complications in patients with nonconvulsive status epilepticus (NCSE) who are followed up in the intensive care unit (ICU), and the impact of these complications on outcome are not well-known. We investigated the complications and their effects on prognosis in NCSE patients. Methods. After reviewing the video-EEG monitoring (VEEGM) reports of all the consecutive patients who were followed up in our ICU between 2009 and 2019, we identified two groups of patients: 1-patients with NCSE (study group) and 2-patients who underwent VEEGM for possible NCSE but did not have ictal recordings (no-NCSE group). Electronic health records were reviewed to identify demographic and clinical data, duration of ICU care, medical and surgical complications, pharmacologic treatment, and outcome. These parameters were compared statistically between the groups. We also investigated the parameters affecting prognosis at discharge. Results. Thirty-two patients with NCSE comprised the study group. Infection developed in 84%. More than half were intubated, had tracheostomy or percutaneous endoscopic gastrostomy application. Refractory NCSE was associated with significantly more frequent complications and worse outcome. There was a higher tendency of infections in the study group (P = .059). Higher organ failure scores and prolonged stay in ICU predicted worse outcome (P < .05). Conclusion. The frequency of complications in patients with NCSE who are cared for in the ICU is considerable. Most of the complications are similar to the other patients in ICU, except for the higher frequency of infections. Increased physician awareness about modifiable parameters and timely interventions might help improve prognosis.

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来源期刊
Clinical EEG and Neuroscience
Clinical EEG and Neuroscience 医学-临床神经学
CiteScore
5.20
自引率
5.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Clinical EEG and Neuroscience conveys clinically relevant research and development in electroencephalography and neuroscience. Original articles on any aspect of clinical neurophysiology or related work in allied fields are invited for publication.
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