观察等待法在直肠癌治疗中的应用综述。

IF 1.8 Q3 ONCOLOGY
Hwa Kyung Byun, Woong Sub Koom
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引用次数: 2

摘要

直肠切除手术后的新辅助治疗一直是局部晚期直肠癌的主要治疗方法。然而,直肠根治性切除术后的功能结果和生活质量仍然不理想。在新辅助治疗后达到病理完全缓解的患者的良好肿瘤预后质疑根治性手术的必要性。观察等待方法是器官保存和避免手术并发症的一种非侵入性治疗方法。在观察和等待方法中,局部晚期直肠癌患者在新辅助治疗后获得良好的临床反应,而不是直肠癌手术。在这篇实践综述中,我们总结了观察与等待方法的主要研究成果,并提供了一种实现观察与等待方法的实用方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A practical review of watch-and-wait approach in rectal cancer.

Rectal resection surgery after neoadjuvant treatment has been the mainstay treatment of locally advanced rectal cancer. However, functional outcomes and quality of life after radical resection of the rectum remain suboptimal. The excellent oncologic outcomes in patients who achieved pathologic complete response after neoadjuvant treatment questioned the need for radical surgery. The watch-and-wait approach is a noninvasive therapeutic alternative for organ preservation and avoiding operative morbidity. In the watch-and-wait approach, patients with locally advanced rectal cancer who achieve excellent clinical response after neoadjuvant treatment undergo active surveillance rather than rectal cancer surgery. In this practical review, we summarized the main results of studies on the watch-and-wait approach and provided a practical method for implementing the watch-and-wait approach.

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来源期刊
CiteScore
3.50
自引率
4.30%
发文量
24
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