Diarrhée Motrice

N.W. Read
{"title":"Diarrhée Motrice","authors":"N.W. Read","doi":"10.1016/S0300-5089(21)00743-4","DOIUrl":null,"url":null,"abstract":"<div><p>The gut is a long convoluted tube, in which food is processed and nutrients, salt and water are absorbed. The degree of absorption depends to a large extent on the degree of contact between the luminal contents and the absorptive epithelium. Motor activity can influence the degree of absorption because it regulates the degree of contact with the epithelium and it may also induce secretion by a reflex mechanism. Many factors that induce diarrhoea are associated with ‘abnormal’ and highly propagative forms of motor activity that can clear material through the gut, allowing insufficient epithelial contact for absorption. These propulsive motor patterns may be provoked by distension of the gut with fluid, but they can also occur in response to diarrhoeogenic factors when there is minimal distension.</p><p>Patients who complain of increased frequency, urgency and incontinence but pass normal stool volumes often have an abnormality in the motor activity of the anorectum. Thus, the generation of abnormal or propagated forms of motor activity must be regarded as an important component of the pathogenesis of all types of diarrhoea and an increased stool volume can be regarded as the end result of a vicious spiral (Figure 12) that may start with a primary abnormality in either motor activity or epithelial transport.</p></div>","PeriodicalId":75717,"journal":{"name":"Clinics in gastroenterology","volume":"15 3","pages":"Pages 657-686"},"PeriodicalIF":0.0000,"publicationDate":"1986-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diarrhée Motrice\",\"authors\":\"N.W. Read\",\"doi\":\"10.1016/S0300-5089(21)00743-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The gut is a long convoluted tube, in which food is processed and nutrients, salt and water are absorbed. The degree of absorption depends to a large extent on the degree of contact between the luminal contents and the absorptive epithelium. Motor activity can influence the degree of absorption because it regulates the degree of contact with the epithelium and it may also induce secretion by a reflex mechanism. Many factors that induce diarrhoea are associated with ‘abnormal’ and highly propagative forms of motor activity that can clear material through the gut, allowing insufficient epithelial contact for absorption. These propulsive motor patterns may be provoked by distension of the gut with fluid, but they can also occur in response to diarrhoeogenic factors when there is minimal distension.</p><p>Patients who complain of increased frequency, urgency and incontinence but pass normal stool volumes often have an abnormality in the motor activity of the anorectum. Thus, the generation of abnormal or propagated forms of motor activity must be regarded as an important component of the pathogenesis of all types of diarrhoea and an increased stool volume can be regarded as the end result of a vicious spiral (Figure 12) that may start with a primary abnormality in either motor activity or epithelial transport.</p></div>\",\"PeriodicalId\":75717,\"journal\":{\"name\":\"Clinics in gastroenterology\",\"volume\":\"15 3\",\"pages\":\"Pages 657-686\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1986-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinics in gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0300508921007434\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0300508921007434","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

肠道是一个长而弯曲的管道,在这里食物被加工,营养物质、盐和水被吸收。吸收程度在很大程度上取决于腔内内容物与吸收上皮之间的接触程度。运动活动可以影响吸收程度,因为它调节与上皮的接触程度,也可能通过反射机制诱导分泌。诱发腹泻的许多因素与“异常”和高度繁殖的运动活动形式有关,这些运动活动可通过肠道清除物质,导致上皮接触不足而无法吸收。这些推进运动模式可能是由肠道液体膨胀引起的,但也可能是对腹泻源性因素的反应,当腹胀最小时。主诉大便频率增加、尿急和大小便失禁但排便量正常的患者,常伴有肛肠运动活动异常。因此,异常或扩展形式的运动活动的产生必须被视为所有类型腹泻发病机制的重要组成部分,并且粪便量增加可被视为恶性循环的最终结果(图12),该恶性循环可能始于运动活动或上皮运输的原发性异常。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diarrhée Motrice

The gut is a long convoluted tube, in which food is processed and nutrients, salt and water are absorbed. The degree of absorption depends to a large extent on the degree of contact between the luminal contents and the absorptive epithelium. Motor activity can influence the degree of absorption because it regulates the degree of contact with the epithelium and it may also induce secretion by a reflex mechanism. Many factors that induce diarrhoea are associated with ‘abnormal’ and highly propagative forms of motor activity that can clear material through the gut, allowing insufficient epithelial contact for absorption. These propulsive motor patterns may be provoked by distension of the gut with fluid, but they can also occur in response to diarrhoeogenic factors when there is minimal distension.

Patients who complain of increased frequency, urgency and incontinence but pass normal stool volumes often have an abnormality in the motor activity of the anorectum. Thus, the generation of abnormal or propagated forms of motor activity must be regarded as an important component of the pathogenesis of all types of diarrhoea and an increased stool volume can be regarded as the end result of a vicious spiral (Figure 12) that may start with a primary abnormality in either motor activity or epithelial transport.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信