探讨预后不良肿瘤患者保留生育能力的死后生殖的复杂性。

IF 2.8 Q2 REPRODUCTIVE BIOLOGY
Alexander Polyakov, Genia Rozen
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引用次数: 0

摘要

近年来,肿瘤患者的生育能力保存(FP)领域有了显著的发展,为危及生命的疾病患者提供了新的可能性。我们赞扬Jones等人对向预后不良的患者提供计划生育进行了全面的伦理审查,并承认其可能带来的潜在益处。在这种情况下,“预后不良”意味着由于癌症进展而死亡的可能性很高。我们强调考虑死后生殖的重要性,包括在伴侣一方或双方去世后使用冷冻保存的配子或胚胎来孕育孩子,Jones等人简要提到了这个话题。死后生育引发了复杂的伦理、后勤和法律问题。讨论了冷冻保存精子和卵母细胞之间的区别,每种情况都提出了独特的挑战。这篇文章还探讨了同性伴侣在死后生育中所面临的复杂性,解决了与供体选择、合法亲子关系和权利有关的问题。法律和监管方面发挥着至关重要的作用,包括获得明确和合法的同意,界定父母的权利,指导代孕法律,以及解决继承和遗产规划问题。道德困境要求医疗保健专业人员确保知情决策,考虑心理影响,并提供替代性家庭建设方案的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the complexities of posthumous reproduction in fertility preservation for oncology patients with poor prognosis.

The field of fertility preservation (FP) for oncology patients has evolved significantly in recent years, offering new possibilities for individuals with life-threatening illnesses. We commend Jones et al. for their comprehensive ethical review of offering FP to patients with poor prognoses, acknowledging the potential benefits that it may bring. "Poor prognosis" in this context implies a high likelihood of death due to cancer progression. We highlight the importance of considering posthumous reproduction, involving the use of cryopreserved gametes or embryos to conceive a child after one or both partners have passed away, a topic briefly mentioned by Jones et al. Posthumous reproduction raises complex ethical, logistical, and legal questions. Distinctions between cryopreserved sperm and oocytes are discussed, with each scenario presenting unique challenges. The article also examines the complexities faced by same-sex couples in posthumous reproduction, addressing issues related to donor selection, legal parentage, and rights. Legal and regulatory aspects play a crucial role, including obtaining clear and legally valid consent, defining parental rights, navigating surrogacy laws, and addressing inheritance and estate planning. Ethical dilemmas require healthcare professionals to ensure informed decision-making, consider psychological impacts, and offer information on alternative family-building options.

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CiteScore
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