多烯紫杉醇黄斑病变

Imran Haq , Sachin Salvi , Lawrence Brown , Ian Rennie , Paul Rundle
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引用次数: 0

摘要

一位56岁的退休剧院护士,患有转移性乳腺癌,自开始服用口服抗有丝分裂化疗药物多西他赛(Taxotere)后,左眼视力下降。最佳矫正视力左眼为6/18,右眼为6/9-1。临床检查和随后的光学相干断层扫描和静脉荧光素血管造影显示药物相关性黄斑病变的证据。右眼未见异常。据我们所知,这是首例多西他赛开始后黄斑病变无黄斑水肿的报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Docetaxel maculopathy

A 56 year old retired theatre nurse who has metastatic breast carcinoma complains of reduced vision in the left eye since being started on Docetaxel (Taxotere), an oral anti-mitotic chemotherapeutic agent. Best corrected visual acuity was 6/18 in the left eye, and 6/9-1 in the right. Clinical examination and subsequent examination with optical coherence tomography and Intravenous Fluorescein angiography revealed evidence suggestive of drug related maculopathy. No abnormal findings were present in the right eye. As far as we are aware, this is the first reported case of maculopathy following commencement of Docetaxel with the absence of macular oedema.

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