Stefan Müller-Hülsbeck, Marcus Both, Nikolas Charalambous, Philipp J. Schäfer, Martin Heller, Thomas Jahnke
{"title":"内窥管处理动脉硬化动脉栓塞和主动脉弓狭窄:一中心分析的中期结果","authors":"Stefan Müller-Hülsbeck, Marcus Both, Nikolas Charalambous, Philipp J. Schäfer, Martin Heller, Thomas Jahnke","doi":"10.1016/j.rontge.2006.05.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To determine mid-term patency rates after endovascular treatment of supraaortic atherosclerotic arterial stenoses and occlusions using percutaneous transluminal angioplasty (PTA) and stent placement.</p></div><div><h3>Patients and Methods</h3><p>During a period of 83 months, 48 patients (18 female, 30 male; mean age 61 years, range 31–82 years) were included into this prospective single-center study. Fifty-five lesions of the brachial and cephalic arteries (subclavian/axillary artery <em>n</em>=42, innominate artery <em>n</em>=7, origin common carotid artery <em>n</em>=6) were treated using PTA (<em>n</em>=38), PTA plus stent (<em>n</em>=11) or primary stent placement (<em>n</em>=6). For anticoagulation, patients received a bolus of heparin (5000<!--> <!-->IU) intraarterially during the intervention followed by intravenous application for 24<!--> <!-->h. At discharge, life-time application of ASA (100<!--> <!-->mg/day) was initiated. Follow-up protocol included clinical examination, colour-coded duplex ultrasound and intraarterial angiography in case of re-stenosis.</p></div><div><h3>Results</h3><p>PTA and stent placement were technically successful in all patients (100%). No major complications occurred. Of seven patients presenting with total occlusions, six were treated with stent placement. Stent implantation was also performed in all lesions located at the origin of the supraaortic arteries (<em>n</em>=6). In 38 lesions, the result of PTA was satisfactory. Mean follow-up time is 22 months (range 1–83 months). During follow-up examinations, re-stenoses occurred in 10 cases (at 1 month <em>n</em>=2, at 6 months <em>n</em>=2, at 12 months <em>n</em>=3, at 24 months <em>n</em>=3). In 9 lesions, re-interventions were performed (PTA <em>n</em>=7; PTA plus stent <em>n</em>=2). According to Kaplan–Meier life-table analysis, cumulative primary and primary assisted patency rates are 69.5% (patients at risk <em>n</em>=15; standard error 9%) and 90.6% (patients at risk <em>n</em>=16; standard error 6.3%) at 20 months, respectively.</p></div><div><h3>Conclusions</h3><p>Endovascular treatment of atherosclerotic obstructive disease in brachial and cephalic arteries is a safe procedure showing promising mid-term patency rates.</p></div>","PeriodicalId":76505,"journal":{"name":"Rontgenpraxis; Zeitschrift fur radiologische Technik","volume":"56 4","pages":"Pages 119-128"},"PeriodicalIF":0.0000,"publicationDate":"2007-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rontge.2006.05.004","citationCount":"10","resultStr":"{\"title\":\"Endovaskuläre Behandlung arteriosklerotisch bedingter arterieller Stenosen und Okklusionen der Aortenbogengefäße: Mittelfristige Ergebnisse einer Ein-Center-Analyse\",\"authors\":\"Stefan Müller-Hülsbeck, Marcus Both, Nikolas Charalambous, Philipp J. Schäfer, Martin Heller, Thomas Jahnke\",\"doi\":\"10.1016/j.rontge.2006.05.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>To determine mid-term patency rates after endovascular treatment of supraaortic atherosclerotic arterial stenoses and occlusions using percutaneous transluminal angioplasty (PTA) and stent placement.</p></div><div><h3>Patients and Methods</h3><p>During a period of 83 months, 48 patients (18 female, 30 male; mean age 61 years, range 31–82 years) were included into this prospective single-center study. Fifty-five lesions of the brachial and cephalic arteries (subclavian/axillary artery <em>n</em>=42, innominate artery <em>n</em>=7, origin common carotid artery <em>n</em>=6) were treated using PTA (<em>n</em>=38), PTA plus stent (<em>n</em>=11) or primary stent placement (<em>n</em>=6). For anticoagulation, patients received a bolus of heparin (5000<!--> <!-->IU) intraarterially during the intervention followed by intravenous application for 24<!--> <!-->h. At discharge, life-time application of ASA (100<!--> <!-->mg/day) was initiated. Follow-up protocol included clinical examination, colour-coded duplex ultrasound and intraarterial angiography in case of re-stenosis.</p></div><div><h3>Results</h3><p>PTA and stent placement were technically successful in all patients (100%). No major complications occurred. Of seven patients presenting with total occlusions, six were treated with stent placement. Stent implantation was also performed in all lesions located at the origin of the supraaortic arteries (<em>n</em>=6). In 38 lesions, the result of PTA was satisfactory. Mean follow-up time is 22 months (range 1–83 months). During follow-up examinations, re-stenoses occurred in 10 cases (at 1 month <em>n</em>=2, at 6 months <em>n</em>=2, at 12 months <em>n</em>=3, at 24 months <em>n</em>=3). In 9 lesions, re-interventions were performed (PTA <em>n</em>=7; PTA plus stent <em>n</em>=2). According to Kaplan–Meier life-table analysis, cumulative primary and primary assisted patency rates are 69.5% (patients at risk <em>n</em>=15; standard error 9%) and 90.6% (patients at risk <em>n</em>=16; standard error 6.3%) at 20 months, respectively.</p></div><div><h3>Conclusions</h3><p>Endovascular treatment of atherosclerotic obstructive disease in brachial and cephalic arteries is a safe procedure showing promising mid-term patency rates.</p></div>\",\"PeriodicalId\":76505,\"journal\":{\"name\":\"Rontgenpraxis; Zeitschrift fur radiologische Technik\",\"volume\":\"56 4\",\"pages\":\"Pages 119-128\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-03-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.rontge.2006.05.004\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rontgenpraxis; Zeitschrift fur radiologische Technik\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0035782006000176\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rontgenpraxis; Zeitschrift fur radiologische Technik","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0035782006000176","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Endovaskuläre Behandlung arteriosklerotisch bedingter arterieller Stenosen und Okklusionen der Aortenbogengefäße: Mittelfristige Ergebnisse einer Ein-Center-Analyse
Objective
To determine mid-term patency rates after endovascular treatment of supraaortic atherosclerotic arterial stenoses and occlusions using percutaneous transluminal angioplasty (PTA) and stent placement.
Patients and Methods
During a period of 83 months, 48 patients (18 female, 30 male; mean age 61 years, range 31–82 years) were included into this prospective single-center study. Fifty-five lesions of the brachial and cephalic arteries (subclavian/axillary artery n=42, innominate artery n=7, origin common carotid artery n=6) were treated using PTA (n=38), PTA plus stent (n=11) or primary stent placement (n=6). For anticoagulation, patients received a bolus of heparin (5000 IU) intraarterially during the intervention followed by intravenous application for 24 h. At discharge, life-time application of ASA (100 mg/day) was initiated. Follow-up protocol included clinical examination, colour-coded duplex ultrasound and intraarterial angiography in case of re-stenosis.
Results
PTA and stent placement were technically successful in all patients (100%). No major complications occurred. Of seven patients presenting with total occlusions, six were treated with stent placement. Stent implantation was also performed in all lesions located at the origin of the supraaortic arteries (n=6). In 38 lesions, the result of PTA was satisfactory. Mean follow-up time is 22 months (range 1–83 months). During follow-up examinations, re-stenoses occurred in 10 cases (at 1 month n=2, at 6 months n=2, at 12 months n=3, at 24 months n=3). In 9 lesions, re-interventions were performed (PTA n=7; PTA plus stent n=2). According to Kaplan–Meier life-table analysis, cumulative primary and primary assisted patency rates are 69.5% (patients at risk n=15; standard error 9%) and 90.6% (patients at risk n=16; standard error 6.3%) at 20 months, respectively.
Conclusions
Endovascular treatment of atherosclerotic obstructive disease in brachial and cephalic arteries is a safe procedure showing promising mid-term patency rates.
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