母体冷反应免疫球蛋白G抗m引起胎儿溶血性疾病的MNS血型系统。

IF 1.1 4区医学 Q4 IMMUNOLOGY

Iranian Journal of Immunology Pub Date : 2023-03-14 DOI:10.22034/iji.2023.93993.2273

Yan-Lian Liang, Yu Shi, Yu-Qing Su, Fan Wu, Yanwen Liang, Xiuchu Fan, Jiansuo Lin, Yi Liu, Peng Long, Jianwei Ren, Shuang Liang

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引用次数: 0

摘要

免疫球蛋白G (IgG)抗m抗体引起的胎儿和新生儿溶血性疾病(HDFN)已报道数例，其中几乎所有与HDFN相关的抗m抗体都发生热反应。在这里，我们报告了两例与冷反应IgG抗m相关的严重hdn。在这两例中，由于胎儿生长迟缓(FGR)的诊断，分别在第33周和第23周终止妊娠。据我们所知，这些是由冷反应的IgG抗m引起的最严重的hdf病例。

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Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus.

Several cases of the hemolytic disease of the fetus and newborn (HDFN) caused by immunoglobulin G (IgG) anti-M antibodies have been reported, in which almost all the HDFN-associated anti-M were warmly reacting. Here we report two cases of severe HDFN associated with cold-reacting IgG anti-M. In both cases, pregnancy was terminated, in weeks 33 and 23 respectively, due to a diagnosis of fetal growth retardation (FGR). To our knowledge, these are the most severe HDFN cases caused by cold-reacting IgG anti-M.

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来源期刊

Iranian Journal of Immunology Medicine-Immunology and Allergy

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Immunology (I.J.I) is an internationally disseminated peer-reviewed publication and publishes a broad range of experimental and theoretical studies concerned with all aspects of immunology.