上肢恶性骨肿瘤的切除-重建

P. Anract (Professeur des Universités, praticien hospitalier), B. Tomeno (Professeur des Universités, praticien hospitalier)
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摘要

恶性骨和软组织肿瘤在上肢较下肢少见(比例为1:2)。它们主要影响肩部,尤其是肱骨近端。约80%的恶性肩关节肿瘤患者可考虑行保肢手术。相反,对于远端恶性肿瘤(肘部或以下)累及骨外组织的患者,通常需要截肢。在治疗肿瘤之前必须进行活组织检查,同时进行旨在评估肿瘤在骨骼和软组织中的扩展、肿瘤与关节、血管和神经之间的关系、区域扩散和潜在转移性疾病的调查。肩胛骨切除术后,肱骨近端悬挂在锁骨或肋骨上。大块的肩胛骨假体或同种异体移植很少使用。当肱骨近端可以切除而不切除三角肌时,可以使用复合三角逆行假体、大块同种异体移植物或复合肱骨假体进行重建。当需要切除三角肌时,进行同种异体和自体移植的肩关节融合术。肱骨骨干切除术后,重建依靠同种异体和自体植骨植入内固定。肘关节重建通常采用关节融合术、大块假体或大块同种异体移植物。为了重建桡骨远端,我们通常将桡骨远端与第一排腕骨进行关节融合术。其他选择包括植入带血管的腓骨移植物和大量同种异体移植物用于关节融合术或关节成形术。切除远端尺骨后,不需要重建。手部的原发性骨恶性肿瘤更为罕见;它们通常涉及掌骨。保守切除很少可行,大多数患者需要完全或部分截肢以获得无肿瘤边缘。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Résections-reconstructions pour tumeurs osseuses malignes du membre supérieur

Malignant bone and soft-tissue tumours are less common in the upper limb than in the lower limb (ratio 1:2). They mainly affect the shoulder, particularly the proximal humerus. Limb-sparing surgery may be considered in about 80% of patients with malignant shoulder tumours. In contrast, in patients with more distal malignancies (at the elbow level, or below) that involve extraosseous tissue, amputation is frequently required. A biopsy must be performed prior to treatment of the tumour, together with investigations aimed at assessing the tumour extension in the bone and soft tissues, the relationships between the tumour and the joints, vessels and nerves, the regional spread, and potential metastatic disease. After scapulectomy, the proximal humerus is suspended to the clavicle or ribs. Massive scapular prostheses or allografts are rarely used. When the proximal humerus can be resected without removing the deltoid muscle, reconstruction can be achieved using a composite inversed Delta prosthesis, a massive allograft, or a composite humeral prosthesis. When deltoid excision is required, scapulohumeral arthrodesis with allogeneic and autologous grafting is performed. After resection of the humeral diaphysis, reconstruction relies on allogeneic and autologous graft implantation with internal fixation. For elbow reconstruction, arthrodesis, massive prosthesis, or massive allograft is generally used. For reconstruction of the distal radius, we usually perform arthrodesis of the distal radius to the first row of carpal bones. Alternatives include implantation of a vascularized fibular graft and massive allografting for arthrodesis or arthroplasty. After resection of the distal ulna, reconstruction is not necessary. Primary bone malignancies of the hand are more rare; they usually involve metacarpal bones. Conservative resection is rarely feasible, and most patients require complete or partial hand amputation to obtain tumour-free margins.

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