Concentrés plaquettaires : technologies, biologie associée, applications cliniques, analyses histologiques

The use of platelet gel as surgical additive is still recent and suffers from the lack of serious investigations as for their biological properties. It highlights the need for rationalized, reproducible and reliable protocols of analysis of the results obtained by addition of these preparations. Because of the total absence of work on the PRF (Platelet-Rich Fibrin), whose action on the osseous remodelling is in theory more significant than that a simple biological adhesive containing fibrin (cPRP: concentrated Platelet-Rich Plasma), we undertook a histological study of bone biopsies obtained from a series of 9 sinus lifts carried out with freeze-dried bone allograft Phœnix from TBF^®, with or without PRF. After four months of maturation, the bone tissue grafted with PRF has acquired an almost superposable architecture with that obtained after 8 months without PRF. Moreover, the quantities of newly formed bone are equivalent between the two protocols. These first results enable us to consider the reduction of the graft maturation time before implantation and grafting with smaller bone harvesting thanks to the addition of PRF.