Salman Mohd, Majaz Qazi, Abrarul Haq, N. Khan, S. Siraj
{"title":"盐酸氯他弗林迷你片的处方、优化及评价","authors":"Salman Mohd, Majaz Qazi, Abrarul Haq, N. Khan, S. Siraj","doi":"10.52711/2231-5713.2022.00002","DOIUrl":null,"url":null,"abstract":"The aim of present research was to develop a mini tablet of Drotaverine hydrocholoride. Mini tablets of Drotaverine hcl were prepared by using various polymers, such as gellan gum and carbopol 940. Mini tablets were evaluated for weight variation, hardness, thickness, friability, drug content, and in-vitro dissolution studies. The prepared mini tablets exhibited satisfactory physic-chemical characteristics. All prepared batches shown good in-vitro dissolution studies. The best result from optimized batches is of F5 which gives drug release 97.72% in 12 h time periods.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Formulation, Optimization and Evaluation of Drotaverine HCl Mini Tablet\",\"authors\":\"Salman Mohd, Majaz Qazi, Abrarul Haq, N. Khan, S. Siraj\",\"doi\":\"10.52711/2231-5713.2022.00002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aim of present research was to develop a mini tablet of Drotaverine hydrocholoride. Mini tablets of Drotaverine hcl were prepared by using various polymers, such as gellan gum and carbopol 940. Mini tablets were evaluated for weight variation, hardness, thickness, friability, drug content, and in-vitro dissolution studies. The prepared mini tablets exhibited satisfactory physic-chemical characteristics. All prepared batches shown good in-vitro dissolution studies. The best result from optimized batches is of F5 which gives drug release 97.72% in 12 h time periods.\",\"PeriodicalId\":8527,\"journal\":{\"name\":\"Asian Journal of Pharmacy and Technology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Pharmacy and Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52711/2231-5713.2022.00002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Pharmacy and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/2231-5713.2022.00002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Formulation, Optimization and Evaluation of Drotaverine HCl Mini Tablet
The aim of present research was to develop a mini tablet of Drotaverine hydrocholoride. Mini tablets of Drotaverine hcl were prepared by using various polymers, such as gellan gum and carbopol 940. Mini tablets were evaluated for weight variation, hardness, thickness, friability, drug content, and in-vitro dissolution studies. The prepared mini tablets exhibited satisfactory physic-chemical characteristics. All prepared batches shown good in-vitro dissolution studies. The best result from optimized batches is of F5 which gives drug release 97.72% in 12 h time periods.
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