阿那白在两种自身炎症性疾病合并患者中的应用:家族性地中海热和痛风

M. Eliseev, O. V. Zheliabina, E. Nasonov, E. Cheremushkina, T. Korotkova, T. S. Panevin
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引用次数: 0

摘要

与家族性地中海热(FMF)一起,它现在被认为是一种自身炎症性疾病和痛风。FMF和痛风发病机制中炎症基本机制的共性预先决定了使用旨在停止和预防癫痫发作的类似疗法(秋水仙碱和IL-1抑制剂)的可能性。一个临床病例是提出描述的FMF和痛风在病人的组合存在。病人开了阿那白,这被证明是有效的治疗FMF和痛风。IL-1抑制剂的指定完全证实了预期:在第一次注射阿那白后,患者关节肿胀和疼痛的强度已经减轻。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The use of Anakinra in a patient with a combination of two autoinflammatory diseases: Familial Mediterranean fever and gout
Along with familial Mediterranean fever (FMF), it is now considered an autoinflammatory disease and gout. The commonality of the basic mechanisms of inflammation underlying the pathogenesis of FMF and gout predetermines the possibility of using similar therapies aimed at stopping and preventing seizures (colchicine and IL-1 inhibitors). A clinical case is presented describing the presence of a combination of FMF and gout in a patient. The patient was prescribed anakinra, which proved to be effective both as a treatment for FMF and gout. The appointment of an IL-1 inhibitor fully justified expectations: already after the first injection of anakinra, the intensity of swelling and pain in the joints decreased in the patient.
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