改良的ASTM F75合金用于髋关节植入物的性能表征

P. F. Yao, S. Li, R. Liu
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引用次数: 0

摘要

ASTM F75是一种低碳CoCrMo合金,几十年来一直被用作髋关节植入材料,但由于金属对金属的承载有限,当股骨头和髋臼杯松动时,ASTM F75植入物可能会失效。因此,提出了一种含有90 wt.% ASTM F75和10 wt.% Cr的改良版ASTM F75合金。模拟人体髋关节植入物的工作环境,研究了两种合金的耐磨性和耐腐蚀性。采用有限元模拟方法研究了采用ASTM F75或改性材料的股骨假体在人体载荷条件下的力学行为。测定了合金的细胞毒性(MTT),并与惰性陶瓷和细胞毒性钴进行了比较。实验和仿真结果表明,该合金比传统髋关节植入材料具有更好的耐磨损和耐腐蚀性能。这两种合金在人体载荷条件下用于股骨植入物时,具有良好的应力和变形性能。这两种合金表现出与惰性陶瓷相似的细胞毒性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Performance Characterization of Modified ASTM F75 Alloy for Hip Implant Application
ASTM F75 is a low-carbon CoCrMo alloy which has been used as hip implant material for decades, but the ASTM F75 implants can fail when the femoral head and the acetabular cup loosen because of limited metal-on-metal bearing. Therefore, a modified version of ASTM F75 alloy which has 90 wt.% ASTM F75 plus 10 wt.% Cr is proposed. The wear and corrosion resistance of both alloys are investigated simulating the working environment of hip implants in human body. The mechanics behavior of the femoral implant under the loading condition in human body with ASTM F75 or modified ASTM F75 material used is studied with FEA simulation. The cytotoxicity (MTT) assays of the alloys are measured and compared to that of inert ceramic and cytotoxic cobalt. The experimental and simulation results show that the proposed alloy exhibits better wear and corrosion resistance than the conventional hip implant material. Both alloys behave well with respect to stress and deformation when used for the femoral implant under the loading condition in human body. These two alloys display similar cytotoxicity performance to inert ceramic.
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