炎症介质在能量代谢中的作用是什么

Simone Fátima Gomes
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引用次数: 8

摘要

亚临床和低强度炎症、氧化应激、高热量和高脂肪饮食模式是肥胖的显著特征。脂肪组织通过其内分泌功能,与IL-4、IL-13、IL-15、IFN-γ等细胞因子的分泌有关,这些细胞因子通过改变生物化学、人体测量和身体成分参数,引发代谢变化,并可能调节能量代谢。本文综述了这些细胞因子与调节能量代谢、诱发或预防肥胖的介质之间关系的科学证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
WHAT IS THE ROLE OF INFLAMMATORY MEDIATORS ON ENERGY METABOLISM
The subclinical and low intensity inflammation, oxidative stress, high calorie and high fat diet patterns are striking features of the obesity. The adipose tissue, through its endocrine function, is associated with the cytokines secretion, such as: IL-4, IL-13, IL-15 and IFN-γ, which trigger metabolic changes and possibly modulate the energy metabolism by modifying the biochemical, anthropometric and body composition parameters. This review summarizes scientific evidences about the relationship between such cytokines and mediators which alter the energy metabolism, predisposing or preventing the obesity.
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