通过检测热效应突破红外显微镜衍射极限

2017 IEEE Photonics Conference (IPC) Part II Pub Date : 2017-10-01 DOI:10.1109/IPCON.2017.8115977

Delong Zhang, Ji‐Xin Cheng

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引用次数: 0

摘要

我们报道了一种亚微米空间分辨率的中红外光热显微镜。这样的性能已经超过了红外显微镜的衍射极限，并允许活细胞和生物体的无标记三维化学成像。观察内源性脂质和外源性药物在单细胞内的分布。

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Beating the diffraction limit in IR microscopy through detecting the thermal effect

We report a mid-infrared photothermal microscope with sub-micron spatial resolution. Such performance has exceeded the diffraction limit of infrared microscopy and allowed label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells were visualized.

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2017 IEEE Photonics Conference (IPC) Part II

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