妊娠期HPV引起的舌癌:诊断和疫苗接种在管理中的作用

P. Tsikouras, A. Bothou, K. Paraskevopoulos, X. Anthoulaki, A. Chalkidou, Ioannis Tsirkas, F. Gaitatzi, M. Koutsogiannis, Stavroglou Athanasia, A. Lazarou, G. Dragoutsos, K. Nikolettos, Panagiotis Petsidis, S. Zervoudis, G. Iatrakis, G. Galazios, Ioannis Astridis, N. Nikolettos, K. Vahtsevanos
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引用次数: 0

摘要

口腔癌通常是鳞状细胞癌。在西方国家,它更常见于舌头,是口腔粘膜最常见的恶性肿瘤之一。鳞状细胞癌的确切病因尚不清楚。有许多风险因素,如化学、生物、自然和其他与文化、习惯、习俗和传统、宗教和环境影响有关的因素,在国家一级,在不同国家有所不同。生物制剂是病毒(如单纯疱疹病毒、人乳头瘤病毒、艾滋病毒)和真菌病。人乳头瘤病毒(HPV),特别是HPV亚型16,在不吸烟的口腔癌年轻人中呈上升趋势。在分子技术的帮助下,世界范围内的流行病学研究无疑表明了人乳头瘤病毒(HPV)在生长鳞状细胞癌中的重要作用。在孕妇恶性肿瘤病例中,舌头的敏感解剖单位引起了重大的生物伦理问题,肿瘤医疗团队必须以细致、敏锐和负责的态度加以解决。9价疫苗可以预防与鳞状细胞癌相关的HPV 16的致癌亚型,这对年轻女性和男性来说可能是有价值的,并且可能在怀孕期间的未来研究后推荐使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
HPV induced tongue cancer in pregnancy: Diagnosis and the role of vaccination in management
Oral cancer is frequently a squamous cell carcinoma. In Western countries it is more commonly found on the tongue and consists one of the most common malignancies in the oral mucosa. The exact causes of squamous cell carcinoma are not known. There are many risk factors such as chemical, biological, natural and other related to culture, habits, customs and traditions, religion and environmental influences at the national level and differ in different nations. Biological agents are viruses (such as the herpes simplex virus, HPV, HIV) and mycoses. Human papillomavirus (HPV), especially HPV subtype 16, is on the rise in young people with oral cancer who are not smokers. Epidemiological studies throughout world with the help of molecular techniques undoubtedly show the crucial importance of human papillomavirus (HPV) in growth squamous cell carcinoma. The sensitive anatomical unit of the tongue in cases of malignancy in pregnant women creates significant bioethical concerns that must be addressed with delicacy, discernment and responsibility by the oncology medical team. The contribution of the 9 valent vaccination, which provides protection against this oncogenic subtype of HPV 16 associated with squamous cell carcinoma, is likely to be valuable to young women and men, and may be recommended after future studies during pregnancy.
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