摩洛哥马拉喀什阿维森纳军事医院耳真菌病流行病学调查

IF 0.8 Q4 PATHOLOGY
Zohair Ait Ouzdi, Y. Ahroui, Y. Zemrani, Y. Darouassi, H. Ammar, E. Mezouari, R. Moutaj
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引用次数: 2

摘要

耳真菌病是一种真菌感染,主要影响外耳,但可以扩散到附近,变得严重。这种疾病的复发和对治疗的抵抗会造成严重的损害。这项工作的目的是首先确定耳真菌病的患病率,然后在第二个地方指定的贡献因素,并描述涉及真菌的频谱。我们于2018年3月至2018年8月在马拉喀什阿维森纳军事医院的寄生虫学和真菌学实验室进行了为期6个月的前瞻性研究。对每个病人,我们都用无菌拭子进行心房取样。对含环己亚胺和不含环己亚胺的沙伯劳德-氯霉素培养基进行了直接检测和培养。真菌的鉴定是基于菌落的宏观、微观和表型特征。我们的研究纳入了67例患者,其中28例阳性,总体患病率为41%,以女性为主。患者的平均年龄为40岁。耳真菌病的发生有多种因素,每日清洁外耳道是最常见的因素(46%),其次是频繁洗澡(35%)。最常见的菌种是黑曲霉(46%)、黄曲霉(35%)和白色念珠菌(17%)。本研究表明耳真菌病在我国人群中耳炎病因学中的重要性。这些感染的管理必须包括真菌学研究,以便建立适合病原体的抗真菌治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiology of Otomycosis at the Military Hospital Avicenne of Marrakech (Morocco)
Otomycosis is a fungal infection mainly affecting the outer ear, but can spread to the in nerear and become severe. The disease can cause a serious damage for its recurrence and resistance to treatment. The purpose of this work is to determine the prevalence of otomycosis in first place, then in second place to specify the contributing factors and to describe the spectrum of fungi involved. We conducted a prospective study over a period of 6 months between March 2018 and August 2018 in laboratory of parasitology and mycology at the Military Hospital Avicenna of Marrakech. Fore ach patient we performed an atrial sampling with sterile swabs. A direct examination and culture on Sabouraud-Chloramphenicol media with and without cycloheximide were carried out. The identification of fungi was based on the macroscopic, microscopic and phenotypic characteristics of colonies. Our study included 67 patients, of which 28 were positive, giving an overall prevalence of 41% with female predominance. The average age of our patients was 40 years old. Many factors enhanced the otomycosis, the daily cleaning of the external ear canal was the most recurrent factor (46%), followed by frequent bathing (35%). The most common species were Aspergillus niger (46%), Aspergillus flavus (35%), and Candida albicans (17%). This study demonstrates the importance of otomycosis in the etiologies of otitis in our population. The management of these infections must include a mycological study in order to establish an antifungal therapy adapted to the pathogen.
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