Bcidp Matthew Song PharmD, Ashley M. Wilde, Sarah E Moore PharmD, Brian C Bohn PharmD, Clayton J Patross, Bryan Denham, Paul S. Schulz, Julio A. Ramirez
{"title":"SARS-CoV-2逆转录酶聚合酶链反应(RT-PCR)假阴性是患者管理和感染预防的重要考虑因素:路易斯维尔COVID-19流行病学研究病例报告","authors":"Bcidp Matthew Song PharmD, Ashley M. Wilde, Sarah E Moore PharmD, Brian C Bohn PharmD, Clayton J Patross, Bryan Denham, Paul S. Schulz, Julio A. Ramirez","doi":"10.18297/jri/vol4/iss1/43","DOIUrl":null,"url":null,"abstract":"We report a case of false-negative SARS-CoV-2 reverse transcriptase-polymerase chain reaction (RT-PCR) on a nasopharyngeal swab. Treating clinicians and infection preven- tionists should maintain a high suspicion for COVID-19 in the appropriate clinical setting despite negative test results. Utilization of chest computed tomography (CT) should be strongly considered in the diagnostic work-up for suspected COVID-19, particularly in areas with limited RT-PCR availabil- ity.","PeriodicalId":91979,"journal":{"name":"The University of Louisville journal of respiratory infections","volume":"47 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"False-negative SARS-CoV-2 Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) is an Important Consideration for Patient Management and Infection Prevention: A Case Report from The Louisville COVID-19 Epidemiology Study\",\"authors\":\"Bcidp Matthew Song PharmD, Ashley M. Wilde, Sarah E Moore PharmD, Brian C Bohn PharmD, Clayton J Patross, Bryan Denham, Paul S. Schulz, Julio A. Ramirez\",\"doi\":\"10.18297/jri/vol4/iss1/43\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We report a case of false-negative SARS-CoV-2 reverse transcriptase-polymerase chain reaction (RT-PCR) on a nasopharyngeal swab. Treating clinicians and infection preven- tionists should maintain a high suspicion for COVID-19 in the appropriate clinical setting despite negative test results. Utilization of chest computed tomography (CT) should be strongly considered in the diagnostic work-up for suspected COVID-19, particularly in areas with limited RT-PCR availabil- ity.\",\"PeriodicalId\":91979,\"journal\":{\"name\":\"The University of Louisville journal of respiratory infections\",\"volume\":\"47 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The University of Louisville journal of respiratory infections\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18297/jri/vol4/iss1/43\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The University of Louisville journal of respiratory infections","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18297/jri/vol4/iss1/43","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
False-negative SARS-CoV-2 Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) is an Important Consideration for Patient Management and Infection Prevention: A Case Report from The Louisville COVID-19 Epidemiology Study
We report a case of false-negative SARS-CoV-2 reverse transcriptase-polymerase chain reaction (RT-PCR) on a nasopharyngeal swab. Treating clinicians and infection preven- tionists should maintain a high suspicion for COVID-19 in the appropriate clinical setting despite negative test results. Utilization of chest computed tomography (CT) should be strongly considered in the diagnostic work-up for suspected COVID-19, particularly in areas with limited RT-PCR availabil- ity.