我在精神病学中使用PET扫描和SPECT

Luca De Peri, Antonio Vita
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引用次数: 0

摘要

在过去的35年里,使用体内脑成像技术PET(正电子发射断层扫描)和SPECT(单光子发射计算机断层扫描)研究精神疾病已经揭示了精神分裂症患者的一些生物学改变。本文描述了这两种成像方式,在潜在的功能原理和应用策略方面,并提供了一个综合的文献综述关于他们在精神分裂症和情绪障碍中的应用。特别强调SPECT和PET的发现在阐明这些疾病的病理生理学和识别可用于评估治疗反应的脑功能潜在生物标志物方面的贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Uso della PET e della SPECT in Psichiatria

In the last 35 years, use of the in vivo brain imaging techniques PET (Positron Emission Tomography) and SPECT (Single Photon Emission Computed Tomography) for the study of psychiatric disorders has revealed several biological alterations in patients with schizophrenia. The present article describes these two imaging modalities, in terms of underlying functional principles and application strategies, and provides a synthetic review of the literature regarding their use in schizophrenia and mood disorders. Particular emphasis is placed on the contribution of SPECT and PET findings in elucidating pathophysiology of these disorders and identifying potential biomarkers of brain function that can be used to assess treatment responses.

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