M. Sasaki , M. Sata , H. Suzuki , Y. Uchimura , S. Murashima , K. Tanaka , N. Uchimura , J. Nakamura , M. Ishibashi , K. Tanikawa
{"title":"急性丙型肝炎抑郁患者接受干扰素治疗时脑血流量的变化","authors":"M. Sasaki , M. Sata , H. Suzuki , Y. Uchimura , S. Murashima , K. Tanaka , N. Uchimura , J. Nakamura , M. Ishibashi , K. Tanikawa","doi":"10.1016/0928-4346(96)00311-8","DOIUrl":null,"url":null,"abstract":"<div><p>Regional cerebral blood flow (rCBF) was measured with single photon emission computed tomography (SPECT) using <em>N</em>-isopropyl-<em>p</em>-[<sup>123</sup>I] iodoamphetamine (<sup>123</sup>I-IMP) in a patient with acute hepatitis C who showed depressive state during interferon therapy. During his depressive state the rCBF was decreased markedly in the inferior frontal cortex. This case suggests that psychotic symptoms during IFN therapy may result from decreased rCBF.</p></div>","PeriodicalId":13746,"journal":{"name":"International Hepatology Communications","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0928-4346(96)00311-8","citationCount":"3","resultStr":"{\"title\":\"Change in cerebral blood flow in an acute hepatitis C patient with depressive state while receiving interferon\",\"authors\":\"M. Sasaki , M. Sata , H. Suzuki , Y. Uchimura , S. Murashima , K. Tanaka , N. Uchimura , J. Nakamura , M. Ishibashi , K. Tanikawa\",\"doi\":\"10.1016/0928-4346(96)00311-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Regional cerebral blood flow (rCBF) was measured with single photon emission computed tomography (SPECT) using <em>N</em>-isopropyl-<em>p</em>-[<sup>123</sup>I] iodoamphetamine (<sup>123</sup>I-IMP) in a patient with acute hepatitis C who showed depressive state during interferon therapy. During his depressive state the rCBF was decreased markedly in the inferior frontal cortex. This case suggests that psychotic symptoms during IFN therapy may result from decreased rCBF.</p></div>\",\"PeriodicalId\":13746,\"journal\":{\"name\":\"International Hepatology Communications\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0928-4346(96)00311-8\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Hepatology Communications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0928434696003118\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Hepatology Communications","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0928434696003118","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Change in cerebral blood flow in an acute hepatitis C patient with depressive state while receiving interferon
Regional cerebral blood flow (rCBF) was measured with single photon emission computed tomography (SPECT) using N-isopropyl-p-[123I] iodoamphetamine (123I-IMP) in a patient with acute hepatitis C who showed depressive state during interferon therapy. During his depressive state the rCBF was decreased markedly in the inferior frontal cortex. This case suggests that psychotic symptoms during IFN therapy may result from decreased rCBF.
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