离子交换膜在制药工业中的应用综述

Ana Morais, B. Batanero, P. Rijo, M. Nicolai
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引用次数: 0

摘要

随着预期寿命的延长,负责不断开发、生产和供应新药以满足人口保健需求的制药部门一直在不断增长。这一情景说明在工业过程中使用一些创新技术是主要的促成因素。在这些技术中,膜分离技术尤为突出。该技术提供了纳米级生物分子的过滤和分离,从而更快地制造过程和更高纯度的最终产品。根据施加的驱动力不同,分离过程涉及不同的方法、进料阶段、不同的孔隙大小或渗透率。在膜分离技术的范围内,电渗析(ED)利用电位差作为驱动力,根据离子的电荷分离离子。从这个意义上说,离子交换膜是净化系统中应用最广泛的分离材料,因为它们具有分离不同电荷种类的优势。本研究评价了两种离子交换膜在某些工业化工过程中作为ED过滤分离器的能力。关键词:离子交换膜;分离技术;制药工业废水处理
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ionic exchange membranes in the pharmaceutical industry – Review
In line with the longer life expectancy, the pharmaceutical sector, responsible for the continuous development, production and supply of new drugs to cope with the population’s healthcare, has been consistently growing. This scenario illustrates the use of some innovative technologies in industrial processes as the major contributing factor. Amongst these technologies, membrane separation technology stands out. This technique affords the filtration and separation of biological molecules at the nanoscale, resulting in a more expedited manufacturing process and a higher purified end product. Depending on the driving force applied, the separation process involves different approaches, feed stages, different pores’ sizes or permeates. In the scope of membrane separation technology, electrodialysis (ED) uses an electrical potential difference as the driving force to separate ions based on their charge. In this sense, ion-exchange membranes are the most widely used separation materials in purifying systems as they have the advantage of partitioning species of different charges. The present study evaluates two ion-exchange membranes' aptitude as separators for ED filtration of some industrial chemical processes. Keywords: Ionic-exchange membranes, separation technology, pharmaceutical industry wastewater treatment, electrodialysis
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