路易体痴呆治疗方法的循证综述

A. Ouf, K. Szigeti
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引用次数: 1

摘要

据估计,全球约15-20%的痴呆症病例受路易体痴呆(DLB)影响。这使得它成为仅次于阿尔茨海默病(AD)的第二大常见痴呆症。矛盾的是,与AD相比,针对DLB复杂症状的临床试验较少。虽然在克服诊断挑战方面取得了实质性进展,但循证治疗仍难以捉摸。在这篇综述中,我们总结了现有的安慰剂对照临床试验,并确定了需要制定治疗策略的领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evidence-Based Review of Therapeutic Approaches in Dementia with Lewy Bodies
Dementia with Lewy Bodies (DLB) is estimated to affect around 15-20% of dementia cases globally. This places it as the second most common type of dementia after Alzheimer’s disease (AD). Paradoxically, clinical trials addressing the complex symptomatology of DLB are sparse compared to AD. While substantial progress has been made in overcoming the diagnostic challenges, evidence-based treatment is elusive. In this review we summarize the available placebo-controlled clinical trials and identify areas of need to develop treatment strategies.
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