Peter N Johnson, Katy Stephens, Philip Barker, Erica Bergeron, Sin Yin Lim, Tracy M Hagemann, Teresa V Lewis, Stephen Neely, Jamie L Miller
{"title":"儿科重症监护室收治的非肥胖儿童与肥胖儿童的持续输液处方模式。","authors":"Peter N Johnson, Katy Stephens, Philip Barker, Erica Bergeron, Sin Yin Lim, Tracy M Hagemann, Teresa V Lewis, Stephen Neely, Jamie L Miller","doi":"10.1055/s-0039-1692669","DOIUrl":null,"url":null,"abstract":"<p><p>This retrospective study compared the continuous infusions prescribed for obese and nonobese children. Ninety-five (13.2%) received an infusion. A greater percentage of obese ( <i>n</i> = 42/168) versus nonobese (53/552) children received infusions, <i>p</i> < 0.01. No difference was noted in the median number of infusions between the obese and nonobese groups, 2 versus 2, <i>p</i> = 0.975. The top 20 prescribed infusions included ten (50%) for sedation/analgesia or neuromuscular blockade and six (30%) for hemodynamic support. A literature search was performed for these 20 agents to determine pharmacokinetics, pharmacodynamics, and dosing in obese children and revealed six studies evaluating fentanyl ( <i>n</i> = 2), midazolam ( <i>n</i> = 1), and propofol ( <i>n</i> = 3).</p>","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"226-232"},"PeriodicalIF":0.0000,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821521/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prescribing Patterns of Continuous Infusions in Nonobese versus Obese Children Admitted to the Pediatric Intensive Care Unit.\",\"authors\":\"Peter N Johnson, Katy Stephens, Philip Barker, Erica Bergeron, Sin Yin Lim, Tracy M Hagemann, Teresa V Lewis, Stephen Neely, Jamie L Miller\",\"doi\":\"10.1055/s-0039-1692669\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This retrospective study compared the continuous infusions prescribed for obese and nonobese children. Ninety-five (13.2%) received an infusion. A greater percentage of obese ( <i>n</i> = 42/168) versus nonobese (53/552) children received infusions, <i>p</i> < 0.01. No difference was noted in the median number of infusions between the obese and nonobese groups, 2 versus 2, <i>p</i> = 0.975. The top 20 prescribed infusions included ten (50%) for sedation/analgesia or neuromuscular blockade and six (30%) for hemodynamic support. A literature search was performed for these 20 agents to determine pharmacokinetics, pharmacodynamics, and dosing in obese children and revealed six studies evaluating fentanyl ( <i>n</i> = 2), midazolam ( <i>n</i> = 1), and propofol ( <i>n</i> = 3).</p>\",\"PeriodicalId\":30555,\"journal\":{\"name\":\"Saude Tecnologia\",\"volume\":\"1 1\",\"pages\":\"226-232\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821521/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Saude Tecnologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0039-1692669\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/6/21 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Saude Tecnologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0039-1692669","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/6/21 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Prescribing Patterns of Continuous Infusions in Nonobese versus Obese Children Admitted to the Pediatric Intensive Care Unit.
This retrospective study compared the continuous infusions prescribed for obese and nonobese children. Ninety-five (13.2%) received an infusion. A greater percentage of obese ( n = 42/168) versus nonobese (53/552) children received infusions, p < 0.01. No difference was noted in the median number of infusions between the obese and nonobese groups, 2 versus 2, p = 0.975. The top 20 prescribed infusions included ten (50%) for sedation/analgesia or neuromuscular blockade and six (30%) for hemodynamic support. A literature search was performed for these 20 agents to determine pharmacokinetics, pharmacodynamics, and dosing in obese children and revealed six studies evaluating fentanyl ( n = 2), midazolam ( n = 1), and propofol ( n = 3).
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
