Clinical parameters and bacteriological evaluation of Acess® as a periodontal therapeutic toothpaste: a non-blinded randomized clinical trial

: Acess Ⓡ toothpaste includes formulation ingredients (latania, chamomile, and myrrh) and re-portedly improves periodontal disease by exerting gingival convergence and anti-inflammatory effects. Although each of these ingredients has antibacterial effects, the effects of Acess Ⓡ on the oral bacteria remain unknown. The present study was aimed at examining the effects of brushing teeth with Acess Ⓡ on periodontal disease and the oral bacterial population. This was a randomized, open-label, parallel, intergroup trial. Each participant was randomly assigned to receive either Acess Ⓡ or a control tooth paste formulation. Participants brushed their teeth twice daily, once in the morning and once in the evening, for five minutes per session. We then assessed clinical parameters such as gingival index (GI), pocket depth (PD), bleeding on probing (BOP) and plaque control record (PCR), and carried out salivary bacteriological examination at baseline and at two and four weeks post-baseline.