卡诺地区急性肾小球肾炎患儿尿路感染的研究

S. Adeleke, M. Asani
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引用次数: 1

摘要

这是一项前瞻性研究47例急性肾小球肾炎在儿科病房见过5年期间,卡诺Aminu Kano教学医院;评估尿路感染的发生率,用氯己定仔细清洁尿孔后取中尿标本。通过耻骨上抽吸收集2岁以下儿童的尿液。尿液培养标本采集于无菌瓶中,采集后24小时内处理。在羊琼脂上孵育48小时。采用椎间盘扩散技术进行抗生素敏感性研究。男性25例(53.2%),女性22例(46.8%),男女比例为1.1:1。患儿平均年龄(+SD)为6.4 + 0.1岁。尿路感染发生率为34%。虽然女性尿路感染发生率(41%)高于男性(16%),但差异无统计学意义(x2 = 2.2, P < 0.05)。大肠杆菌(62.5%)、肺炎克雷伯菌(25%)和金黄色葡萄球菌(12.5%)是最常见的分离菌。这些细菌分离株对氧氟沙星、头孢曲松和龙生素表现出明显的体外敏感性。因此,对肾小球肾炎患儿进行尿路感染筛查非常重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Urinary Tract Infection in Children with Acute Glomerulonephritis in Kano
This is a prospective study of 47 cases of acute glomerunephritis seen in paediatric ward of Aminu Kano Teaching Hospital, Kano over a 5year period; they were evaluated for prevalence of urinary tract infection, urine specimen were obtained by midstream urine following careful cleaning of the orifices with chlorhexidine. Urine was collected from children less than 2years by suprapubic aspiration. Urine culture specimen was collected in sterile bottles and was processed within 24hours of collection. Specimen was incubated on sheep agar for 48hours. Antibiotic sensitivity studies were done using disc diffusion technique. There were 25(53.2%) males and 22(46.8) females giving male to female ratio of 1.1:1. The mean age (+SD) of the children was 6.4 + 0.1years. The prevalence of urinary tract infection was 34%. Although the incidence of UTI was higher in females (41%) than in males (16%), the difference was not statistically significant (x2 = 2.2, P>0.05). Escherichia coli (62.5%), Klebsiella pneumoniae (25%) and Staphylococcus aureu s (12.5%) were the commonest bacterial isolates. These bacterial isolates demonstrated appreciable invitro sensitivity to ofloxacin, ceftriaxone and genticin. It is therefore important to screen for UTI in children presenting with glomerulonephritis.
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