伊巴丹大学附属医院放射肿瘤科鼻咽癌谱分析

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
A. Isah, U. Aliyu, A. Adenipekun, Oladapo Cambell, U. Ango
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引用次数: 0

摘要

背景:鼻咽癌最初在尼日利亚被认为是一种不常见的疾病,但最近的研究表明,该疾病的发病率稳步增加,由于出现较晚,发病率和死亡率也随之增加。目的:探讨鼻咽癌患者的临床表现及转诊模式。背景和设计:这是一项对2000年至2009年Ibadan放射肿瘤科鼻咽癌患者的回顾性研究。方法和材料:采用数据提取表检索患者的生物资料、临床病理表现和转诊部位,随后使用Microsoft Excel(2013)进行分析。使用的统计分析:这是一种描述性分析。结果:在研究期间共分析了205例经组织学证实的鼻咽癌患者。患者平均年龄41.7岁,其中男性144例(70.2%),女性61例(29.8%)。最常见的主诉是颈部淋巴结病,占98.5%,其次是鼻阻塞、鼻溢液和鼻出血,分别占82.0%、78.0%和51.2%。未分化癌是最常见的组织学类型(68.8%)。大多数患者为公务员(33.2%)。大多数患者(43.4%)没有明确吸烟和饮酒的习惯。在本研究中,大多数患者(122例,59.5%)摄入了熏鱼。大部分患者来自南部地区,这与伯基特淋巴瘤的地理分布相吻合;因此,爱泼斯坦-巴尔病毒有可能是致病因子之一。没有患者出现I期疾病,而大多数患者出现III期疾病129(62.9%)。结论:鼻咽癌是常见病。颈部淋巴结病变,鼻阻塞,组织学未分化,晚期就诊为常见病。病人来自全国各地。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spectrum of nasopharyngeal cancers seen in the department of radiation oncology university college hospital, Ibadan
Context: Nasopharyngeal cancers were initially thought to be an uncommon disease in Nigeria, but recent studies have shown a steady increase in the incidence of the disease with an associated increase in morbidity and mortality due to late presentation. Aims: The aims are to evaluate the mode of presentation and referral pattern of nasopharyngeal cancer patients seen. Settings and Design: This was a retrospective review of patients with nasopharyngeal cancer seen in the department of Radiation Oncology U.C.H. Ibadan from 2000 to 2009. Methods and Material: Patients' biodata, clinical–pathologic presentation, and site of referral were retrieved using data extraction form and subsequently analyzed using Microsoft Excel (2013). Statistical Analysis Used: It is a descriptive analysis. Results: A total of 205 patients with histologically confirmed nasopharyngeal cancer seen during the study period were analyzed. The mean age of the patients was 41.7 years with 144 (70.2%) males and 61 (29.8%) females. The commonest presenting complaint was cervical lymphadenopathy in 98.5% of patients followed by nasal blockade, nasal discharge, and epistaxis with 82.0%, 78.0%, and 51.2%, respectively. Undifferentiated carcinoma was the commonest histologic type (68.8%). Majority of patients were civil servants (33.2%). The habit of smoking and alcohol ingestion was unspecified in majority of patients (43.4%). Ingestion of smoked fish has been found in majority of patients (122, 59.5%) with the disease in this study. Most of the patients came from southern part of the country which coincides with the geographic distribution of Burkitt's lymphoma; hence, the possibility of Epstein–Barr virus as one of the likely causative agents. None of the patients presented with stage I disease, while most patients presented at stage III 129 (62.9%). Conclusions: Nasopharyngeal cancer is common. Cervical lymphadenopathy, nasal blockade with undifferentiated histology, and late presentation were the norm. Referrals were from all the regions of the country.
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来源期刊
Nigerian Journal of Basic and Clinical Sciences
Nigerian Journal of Basic and Clinical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
0.20
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