伊斯法罕省慢性肾脏疾病:一项基于人群的筛查研究的行动计划

IF 0.8 4区 医学 Q4 UROLOGY & NEPHROLOGY
Iranian journal of kidney diseases Pub Date : 2022-11-01
Firouzeh Moeinzadeh, Marjan Mansourian, Mojgan Mortazavi, Shiva Seirafian, Shahrzad Shahidi, Zahra Tasdighi, Sahar Vahdat, Shahram Taheri, Mohammad Hossein Rouhani, Mohammad Saleki, Mostafa Rezaei, Mohammad Hossein Masoudi, Zahra Zamani, Nahid Rafie
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引用次数: 0

摘要

本研究旨在探讨伊朗伊斯法罕省成年人群中慢性肾脏疾病(CKD)及其不同阶段的患病率,以及CKD相关变量。方法:在2017年至2019年的横断面研究中招募年龄≥18岁的成年人。数据包括人口统计学,人体测量学和实验室结果从每个受试者收集。采用慢性肾脏疾病-流行病学协作(CKD- epi)方程估计肾小球滤过率(eGFR),并利用eGFR和UACR值确定CKD的分期。结果:共分析了3374名受试者的数据。参与者的平均年龄为49.3±14.09岁,其中59.3%为女性。CKD患病率为18.5%。只有0.25和3.5%的患者处于CKD 3期和4期,而大多数患者处于CKD 2期(7.6%)和1期(7.1%)。与健康参与者相比,CKD患者大多食用精制谷物饮食,使用较少的乳制品。变量包括收缩压(OR = 1.018;P < 0.001),舒张压(OR = 1.005;P < 0.05),空腹血糖(OR = 1.011;P < 0.001),女性(OR = 1.319;P < 0.05),体重指数(OR = 1.030;P < 0.05)、婚姻状况(OR = 1.335;P < 0.05),吸烟(OR = 1.529;在logistic回归分析中,P < 0.05)与CKD风险增加显著相关。结论:根据我们的研究结果,CKD的患病率,特别是1期和2期,在伊朗中部地区相当高。这些发现有助于我们改善CKD患者的筛查,并进行更大规模的研究,以确定未来的挑战。DOI: 10.52547 / ijkd.7201。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chronic Kidney Disease in Isfahan Province, Action Plan for Screening in A Population-based Study.

Introduction: We intended to explore the prevalence of chronic kidney disease (CKD) and its different stages, as well as CKD associated variables in the adult population in Isfahan province, Iran.

Methods: Adults aged ≥ 18 were recruited in a cross-sectional study from 2017 to 2019. Data including demographics, anthropometrics, and laboratory findings were collected from each subject. The equation of chronic kidney disease- Epidemiology Collaboration (CKD-EPI) was used to estimate glomerular filtration rate (eGFR), and eGFR and UACR values were utilized to determine the stages of CKD.

Results: Data from a total of 3374 subjects was analyzed. The mean age of participants was 49.3 ± 14.09 years and 59.3% were female. The prevalence of CKD was 18.5%. Only 0.25 and 3.5% of the population were in CKD stage 3 and 4, while most of the patients were in CKD stage 2 (7.6%) and stage 1 (7.1%). CKD patients were mostly on refined grains diet and used lesser dairy products compared to healthy participants. Variables including systolic blood pressure (OR = 1.018; P < .001), diastolic blood pressure (OR = 1.005; P < .05), fasting blood sugar (OR = 1.011; P < .001), female sex (OR = 1.319; P < .05), body mass index (OR = 1.030; P < .05), married status (OR = 1.335; P < .05), and smoking (OR = 1.529; P < .05) were significantly associated with increased risk of CKD in the logistic regression analysis.

Conclusion: According to our results, the prevalence of CKD, especially stages 1 and 2, is quite high in central part of Iran. These findings help us to improve the screening for CKD patients and perform larger scale studies to identify the challenges ahead.  DOI: 10.52547/ijkd.7201.

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来源期刊
Iranian journal of kidney diseases
Iranian journal of kidney diseases UROLOGY & NEPHROLOGY-
CiteScore
2.50
自引率
0.00%
发文量
43
审稿时长
6-12 weeks
期刊介绍: The Iranian Journal of Kidney Diseases (IJKD), a peer-reviewed journal in English, is the official publication of the Iranian Society of Nephrology. The aim of the IJKD is the worldwide reflection of the knowledge produced by the scientists and clinicians in nephrology. Published quarterly, the IJKD provides a new platform for advancement of the field. The journal’s objective is to serve as a focal point for debates and exchange of knowledge and experience among researchers in a global context. Original papers, case reports, and invited reviews on all aspects of the kidney diseases, hypertension, dialysis, and transplantation will be covered by the IJKD. Research on the basic science, clinical practice, and socio-economics of renal health are all welcomed by the editors of the journal.
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