褪黑素和美金刚作为新组合药物Miladean®的药代动力学和药物相互作用的研究

Clinical pharmacology and therapy Pub Date : 2023-05-21 DOI:10.32756/0869-5490-2023-2-59-65

A. Goncharov, A. Grigoriev, A. Globenko, I. Goncharov, K. A. Muratov, A. Sidorova, A. A. Nikitin, A. Kapashin, O. Kovchan, A. I. Bashkatova, M. Pasko

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引用次数: 0

摘要

比较研究药物Miladean®口服分散片3mg + 5mg(俄罗斯JSC Valenta Pharm)与参比产品Akatinol Memantine 10mg薄膜包衣片(德国Merz Pharma GmbH & Co. KGaA)和Melaxen 3mg薄膜包衣片(美国Unipharm Inc.)的药代动力学和药物相互作用。

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Investigation of pharmacokinetics and drug-drug interactions of melatonin and memantine as components of the new original combination drug Miladean®

To compare pharmacokinetics and evaluate drug-drug interactions of the studied drug Miladean® oral dispersible tablets 3 mg + 5 mg (JSC Valenta Pharm, Russia) and reference products Akatinol Memantine 10 mg film-coated tablets (Merz Pharma GmbH & Co. KGaA, Germany) and Melaxen 3 mg film-coated tablets (Unipharm Inc., USA).

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Clinical pharmacology and therapy

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