Xiaojun Yu, Razina Z. Seeni, Linbo Liu, Chenjie Xu
{"title":"利用光学相干层析成像技术表征聚合物微针的膨胀特性","authors":"Xiaojun Yu, Razina Z. Seeni, Linbo Liu, Chenjie Xu","doi":"10.1109/CLEOPR.2017.8118613","DOIUrl":null,"url":null,"abstract":"We report on noninvasive characterization of MNs' real-time swelling property in mice-skin using a lab-built micro-optical coherence tomography (μOCT). Specifically, we propose to encapsulate the iron-oxide (Fes3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-time temporal swelling behaviors in mice-skin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using μOCT.","PeriodicalId":6655,"journal":{"name":"2017 Conference on Lasers and Electro-Optics Pacific Rim (CLEO-PR)","volume":"8 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography\",\"authors\":\"Xiaojun Yu, Razina Z. Seeni, Linbo Liu, Chenjie Xu\",\"doi\":\"10.1109/CLEOPR.2017.8118613\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We report on noninvasive characterization of MNs' real-time swelling property in mice-skin using a lab-built micro-optical coherence tomography (μOCT). Specifically, we propose to encapsulate the iron-oxide (Fes3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-time temporal swelling behaviors in mice-skin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using μOCT.\",\"PeriodicalId\":6655,\"journal\":{\"name\":\"2017 Conference on Lasers and Electro-Optics Pacific Rim (CLEO-PR)\",\"volume\":\"8 1\",\"pages\":\"1-2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2017 Conference on Lasers and Electro-Optics Pacific Rim (CLEO-PR)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/CLEOPR.2017.8118613\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 Conference on Lasers and Electro-Optics Pacific Rim (CLEO-PR)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CLEOPR.2017.8118613","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography
We report on noninvasive characterization of MNs' real-time swelling property in mice-skin using a lab-built micro-optical coherence tomography (μOCT). Specifically, we propose to encapsulate the iron-oxide (Fes3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-time temporal swelling behaviors in mice-skin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using μOCT.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
