miRNA-205:未来肝脏疾病治疗分子

Future drug discovery Pub Date : 2023-01-01 DOI:10.4155/fdd-2022-0012

Marco Cabrera, Meghana Kolli, Meena Jaggi, Subhash C Chauhan, Murali M Yallapu

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miRNA-205: a future therapeutic molecule for liver diseases.

study results suggest that miR-205 / NEU1 can be a viable therapeutic target for treatment of NAFLD. In the series of experiments conducted on mouse models, it was found that miR-205 has an effect on transcription factor ZEBI, which has a role in liver metabolism and insulin resistance [20] . On the other hand, when NZ10 mice were predisposed with obesity, Type 2 diabetes and hepatic steatosis; fed with high protein ﬁsh oil diet and examined for the biochemical and physical functions, results showed that the diet prevented steatosis and reduced serum cholesterol and triglycerides

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Future drug discovery

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14 weeks