在Parnaíba, Piauí市接种sars-cov-2疫苗后的神经系统不良事件

Edmar José Fortes Júnior, Francisco Ricardo Nascimento Freitas, Francisco Lukas Rodrigues Martins, Ane Kássia de Carvalho Barbosa, Thyago Layron Sampaio de Abreu, Hildnel Rodrigues Leal Silva, Rodrigo Campelo de Moura Fé
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摘要

2019年底,一种后来被称为COVID-19的新疾病在中国湖北省武汉市出现,由一种名为新型冠状病毒或SARS-CoV-2的病毒引起。这种感染已在全球蔓延,造成许多人死亡,然而,在2020年底,第一批针对这种新病毒的疫苗出现了,并得到监管机构的批准,认为它是有效和安全的。然而,自免疫接种开始以来,在普通人群中有很多关于疫苗功效低以及与疫苗接种后严重不良事件(包括死亡)相关的猜测。此外,文献强调神经系统表现是AEFI的主要来源之一。目的:因此,本研究的目的是调查Parnaíba, Piauí市接种Sars-CoV-2疫苗后神经系统不良事件的发生情况。方法采用横断面、观察性、描述性和流行病学定量研究方法。数据收集自巴西国家秘书处Saúde Piauí的信息系统(SI-EAPV),收集时间为2021年1月(巴西开始接种COVID-19疫苗之日)至2021年9月。研究人群集中在巴西Piauí州的Parnaíba市。根据巴西地理研究所Estatística (IBGE)的数据,该城市的人口估计为153,863人。因变量是作为结果的神经系统表现的存在:是/否。分析的其他变量包括肤色/种族、性别和所使用疫苗的描述。(也可以查看完整的摘要,请查看PDF)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurological adverse events after vaccination against sars-cov-2 in the municipality of Parnaíba, Piauí
Introduction At the end of 2019, a new disease that would come to be known as COVID-19 emerged in Wuhan, Hubei province, China, caused by a virus called novel coronavirus or SARS-CoV-2. The infection has spread worldwide, causing many deaths, however, at the end of 2020, the first vaccines against this new virus appeared, approved by regulatory bodies as being effective and safe. However, since the beginning of immunization, there has been much speculation within the general population both about the supposed low efficacy and the correlation with serious post-vaccination adverse events (APVE), including deaths. Furthermore, it is highlighted in the literature that neurological manifestations are one of the main sources of AEFI. Objective: Therefore, the objective of this study is post-vaccination adverse events against covid-19 in the municipality of Parnaíba, Piauí. Objectives 1) Investigate the occurrence of post-vaccination adverse events of a neurological nature of vaccination against Sars-CoV-2 in the municipality of Parnaíba, Piauí. Methods This is a cross-sectional, observational, descriptive and epidemiological quantitative study. Data were collected from the Information Sistema de Informação de Eventos Adversos Pós-Vacinação (SI-EAPV) of Secretaria de Estado da Saúde do Piauí, in the period from January 2021 (date of the beginning of vaccination against COVID-19 in Brazil) to September 2021. The study population was concentrated in the municipality of Parnaíba, located in the state of Piauí, Brazil. According to the Instituto Brasileiro de Geografia e Estatística (IBGE), the estimated population for the municipality in question is 153,863 people. The dependent variable is the presence of neurological manifestation as an outcome: yes/no. The other variables analyzed were color/race, sex and the description of the vaccine used.   (Too see the complete abstract, please, check out the PDF).       
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