ENISI Visual,一个基于代理的模拟肠道免疫的模拟器

Yongguo Mei, R. Hontecillas, Xiaoying Zhang, K. Bisset, S. Eubank, S. Hoops, M. Marathe, J. Bassaganya-Riera
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引用次数: 18

摘要

本文介绍了ENISI Visual,一个基于agent的模拟肠道对肠道病原体免疫的模拟器。胃肠道系统是人体吸收食物和其他营养的重要系统,肠道免疫是人体免疫系统的重要组成部分。ENISI Visual提供高质量的可视化,用户可以控制初始细胞浓度和模拟速度,拍摄快照和录制视频。单元格用不同的图标表示,图标会随着状态的变化而改变颜色。用户可以实时观察免疫反应,包括细胞募集、细胞因子和趋化因子的分泌和消散、随机或趋化运动、细胞间相互作用和状态变化。案例研究清楚地表明,用户可以使用ENISI Visual来开发模型并运行新颖而富有洞察力的计算机实验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ENISI Visual, an agent-based simulator for modeling gut immunity
This paper presents ENISI Visual, an agent-based simulator for modeling gut immunity to enteric pathogens. Gastrointestinal systems are important for in-taking food and other nutritions and gut immunity is an important part of human immune system. ENISI Visual provides quality visualizations and users can control initial cell concentrations and the simulation speed, take snapshots, and record videos. The cells are represented with different icons and the icons change colors as their states change. Users can observe real-time immune responses, including cell recruitment, cytokine and chemokine secretion and dissipation, random or chemotactic movement, cell-cell interactions, and state changes. The case study clearly shows that users can use ENISI Visual to develop models and run novel and insightful in silico experiments.
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